Antiviral Effects of Green Tea EGCG and Its Potential Application against COVID-19

(–)-Epigallocatechin-3-<i>O</i>-gallate (EGCG), the most abundant component of catechins in tea (<i>Camellia sinensis</i> (L.) O. Kuntze), plays a role against viruses through inhibiting virus invasiveness, restraining gene expression and replication. In this paper, the antiv...

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Main Authors: Ying-Qi Wang, Qing-Sheng Li, Xin-Qiang Zheng, Jian-Liang Lu, Yue-Rong Liang
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/13/3962
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author Ying-Qi Wang
Qing-Sheng Li
Xin-Qiang Zheng
Jian-Liang Lu
Yue-Rong Liang
author_facet Ying-Qi Wang
Qing-Sheng Li
Xin-Qiang Zheng
Jian-Liang Lu
Yue-Rong Liang
author_sort Ying-Qi Wang
collection DOAJ
description (–)-Epigallocatechin-3-<i>O</i>-gallate (EGCG), the most abundant component of catechins in tea (<i>Camellia sinensis</i> (L.) O. Kuntze), plays a role against viruses through inhibiting virus invasiveness, restraining gene expression and replication. In this paper, the antiviral effects of EGCG on various viruses, including DNA virus, RNA virus, coronavirus, enterovirus and arbovirus, were reviewed. Meanwhile, the antiviral effects of the EGCG <i>epi</i>-isomer counterpart (+)-gallocatechin-3-<i>O</i>-gallate (GCG) were also discussed.
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spelling doaj.art-3247f8a53cde4926b4b7163ebeff5fa72023-11-22T02:06:22ZengMDPI AGMolecules1420-30492021-06-012613396210.3390/molecules26133962Antiviral Effects of Green Tea EGCG and Its Potential Application against COVID-19Ying-Qi Wang0Qing-Sheng Li1Xin-Qiang Zheng2Jian-Liang Lu3Yue-Rong Liang4Tea Research Institute, Zhejiang University, Hangzhou 310058, ChinaInstitute of Sericulture and Tea, Zhejiang Academy of Agricultural Sciences, Hangzhou 310000, ChinaTea Research Institute, Zhejiang University, Hangzhou 310058, ChinaTea Research Institute, Zhejiang University, Hangzhou 310058, ChinaTea Research Institute, Zhejiang University, Hangzhou 310058, China(–)-Epigallocatechin-3-<i>O</i>-gallate (EGCG), the most abundant component of catechins in tea (<i>Camellia sinensis</i> (L.) O. Kuntze), plays a role against viruses through inhibiting virus invasiveness, restraining gene expression and replication. In this paper, the antiviral effects of EGCG on various viruses, including DNA virus, RNA virus, coronavirus, enterovirus and arbovirus, were reviewed. Meanwhile, the antiviral effects of the EGCG <i>epi</i>-isomer counterpart (+)-gallocatechin-3-<i>O</i>-gallate (GCG) were also discussed.https://www.mdpi.com/1420-3049/26/13/3962EGCGtea polyphenolantiviralCOVID-19SARS-CoV
spellingShingle Ying-Qi Wang
Qing-Sheng Li
Xin-Qiang Zheng
Jian-Liang Lu
Yue-Rong Liang
Antiviral Effects of Green Tea EGCG and Its Potential Application against COVID-19
Molecules
EGCG
tea polyphenol
antiviral
COVID-19
SARS-CoV
title Antiviral Effects of Green Tea EGCG and Its Potential Application against COVID-19
title_full Antiviral Effects of Green Tea EGCG and Its Potential Application against COVID-19
title_fullStr Antiviral Effects of Green Tea EGCG and Its Potential Application against COVID-19
title_full_unstemmed Antiviral Effects of Green Tea EGCG and Its Potential Application against COVID-19
title_short Antiviral Effects of Green Tea EGCG and Its Potential Application against COVID-19
title_sort antiviral effects of green tea egcg and its potential application against covid 19
topic EGCG
tea polyphenol
antiviral
COVID-19
SARS-CoV
url https://www.mdpi.com/1420-3049/26/13/3962
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AT qingshengli antiviraleffectsofgreenteaegcganditspotentialapplicationagainstcovid19
AT xinqiangzheng antiviraleffectsofgreenteaegcganditspotentialapplicationagainstcovid19
AT jianlianglu antiviraleffectsofgreenteaegcganditspotentialapplicationagainstcovid19
AT yuerongliang antiviraleffectsofgreenteaegcganditspotentialapplicationagainstcovid19