Association of decreases in PM2.5 levels due to the implementation of environmental protection policies with the incidence of obesity in adolescents: A prospective cohort study
Aims: To explore the association between decreased levels of particulate matter (≤2.5 µm; PM2.5) due to the implementation of environmental protection policies and the incidence of obesity in adolescents in Chongqing, China through a prospective cohort study. Methods: A total of 2105 children (52.02...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-12-01
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| Series: | Ecotoxicology and Environmental Safety |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S014765132201051X |
| _version_ | 1828098418186125312 |
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| author | Xiaohua Liang Fangchao Liu Fengchao Liang Yanling Ren Xian Tang Shunqing Luo Daochao Huang Wei Feng |
| author_facet | Xiaohua Liang Fangchao Liu Fengchao Liang Yanling Ren Xian Tang Shunqing Luo Daochao Huang Wei Feng |
| author_sort | Xiaohua Liang |
| collection | DOAJ |
| description | Aims: To explore the association between decreased levels of particulate matter (≤2.5 µm; PM2.5) due to the implementation of environmental protection policies and the incidence of obesity in adolescents in Chongqing, China through a prospective cohort study. Methods: A total of 2105 children (52.02% male; aged 7.33 ± 0.60 years at baseline) were enrolled from the Chongqing Children’s Health Cohort. A mixed linear regression model was used to analyse the relationships of PM2.5 levels with obesity indicators after adjusting for covariates. Additionally, a Poisson regression model was used to determine the relationship between PM2.5 exposure and the incidence of overweight/obesity. Results: The average PM2.5 exposure levels from participant conception to 2014, from 2015 to 2017, and from 2018 to 2019 were 66.64 ± 5.33 μg/m3, 55.49 ± 3.78 μg/m3, and 42.50 ± 1.87 μg/m3, respectively; these levels significantly decreased over time (P < 0.001). Throughout the entire follow-up period, the incidence of overweight/obesity after a ≥ 25 μg/m3 decrease in the PM2.5 level was 4.57% among females; this incidence was the lowest among females who experienced remarkable decreases in PM2.5 exposure. A 1-µg/m3 decrease in the PM2.5 level significantly decreased the body mass index (BMI), BMI z score (BMIz), and weight of adolescents (all P < 0.001). Compared with a < 20-μg/m3 decrease in the PM2.5 level, a ≥ 25-μg/m3 decrease protected against increased BMI (net difference= −0.93; 95% confidence interval [CI]: (−1.23,−0.63) kg/m2), BMIz (−0.28 (−0.39, −0.17)), weight (−1.59 (−2.44, −0.74) kg), and incidence of overweight/obesity (0.48 (0.37, 0.62), P < 0.001). Moreover, compared with a < 20-μg/m3 decrease in the PM2.5 level, a ≥ 25-μg/m3 decrease resulted in significant absolute differences in BMI (−1.26 (−1.56, −0.96) kg/m2), BMIz (−0.53 (−0.65, −0.40)) and weight (−3.01 (−3.8, −2.19) kg) (all P < 0.001). Conclusions: This study showed the etiological relevance of declining PM2.5 concentrations for the incidence of obesity in children and adolescents, suggesting that controlling ambient air pollutants may prevent the development of obesity in this age group. Continuous implementation of environmental protection policies in China has led to substantial health benefits. |
| first_indexed | 2024-04-11T08:02:27Z |
| format | Article |
| id | doaj.art-32488dc3c68548ebbf281baf6c667e58 |
| institution | Directory Open Access Journal |
| issn | 0147-6513 |
| language | English |
| last_indexed | 2024-04-11T08:02:27Z |
| publishDate | 2022-12-01 |
| publisher | Elsevier |
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| series | Ecotoxicology and Environmental Safety |
| spelling | doaj.art-32488dc3c68548ebbf281baf6c667e582022-12-22T04:35:42ZengElsevierEcotoxicology and Environmental Safety0147-65132022-12-01247114211Association of decreases in PM2.5 levels due to the implementation of environmental protection policies with the incidence of obesity in adolescents: A prospective cohort studyXiaohua Liang0Fangchao Liu1Fengchao Liang2Yanling Ren3Xian Tang4Shunqing Luo5Daochao Huang6Wei Feng7Department of Clinical Epidemiology and Biostatistics, Children’s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing 400016, China; Correspondence to: 136 2nd Street, Yuzhong District, Chongqing 400014, China.Department of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, ChinaSchool of Public Health and Emergency Management, Southern University of Science and Technology, Shenzhen 518055, ChinaDepartment of Clinical Epidemiology and Biostatistics, Children’s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing 400016, ChinaDepartment of Clinical Epidemiology and Biostatistics, Children’s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing 400016, ChinaDepartment of Clinical Epidemiology and Biostatistics, Children’s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing 400016, China; Department of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China; School of Public Health and Emergency Management, Southern University of Science and Technology, Shenzhen 518055, ChinaDepartment of Clinical Epidemiology and Biostatistics, Children’s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing 400016, ChinaDepartment of Clinical Epidemiology and Biostatistics, Children’s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing 400016, ChinaAims: To explore the association between decreased levels of particulate matter (≤2.5 µm; PM2.5) due to the implementation of environmental protection policies and the incidence of obesity in adolescents in Chongqing, China through a prospective cohort study. Methods: A total of 2105 children (52.02% male; aged 7.33 ± 0.60 years at baseline) were enrolled from the Chongqing Children’s Health Cohort. A mixed linear regression model was used to analyse the relationships of PM2.5 levels with obesity indicators after adjusting for covariates. Additionally, a Poisson regression model was used to determine the relationship between PM2.5 exposure and the incidence of overweight/obesity. Results: The average PM2.5 exposure levels from participant conception to 2014, from 2015 to 2017, and from 2018 to 2019 were 66.64 ± 5.33 μg/m3, 55.49 ± 3.78 μg/m3, and 42.50 ± 1.87 μg/m3, respectively; these levels significantly decreased over time (P < 0.001). Throughout the entire follow-up period, the incidence of overweight/obesity after a ≥ 25 μg/m3 decrease in the PM2.5 level was 4.57% among females; this incidence was the lowest among females who experienced remarkable decreases in PM2.5 exposure. A 1-µg/m3 decrease in the PM2.5 level significantly decreased the body mass index (BMI), BMI z score (BMIz), and weight of adolescents (all P < 0.001). Compared with a < 20-μg/m3 decrease in the PM2.5 level, a ≥ 25-μg/m3 decrease protected against increased BMI (net difference= −0.93; 95% confidence interval [CI]: (−1.23,−0.63) kg/m2), BMIz (−0.28 (−0.39, −0.17)), weight (−1.59 (−2.44, −0.74) kg), and incidence of overweight/obesity (0.48 (0.37, 0.62), P < 0.001). Moreover, compared with a < 20-μg/m3 decrease in the PM2.5 level, a ≥ 25-μg/m3 decrease resulted in significant absolute differences in BMI (−1.26 (−1.56, −0.96) kg/m2), BMIz (−0.53 (−0.65, −0.40)) and weight (−3.01 (−3.8, −2.19) kg) (all P < 0.001). Conclusions: This study showed the etiological relevance of declining PM2.5 concentrations for the incidence of obesity in children and adolescents, suggesting that controlling ambient air pollutants may prevent the development of obesity in this age group. Continuous implementation of environmental protection policies in China has led to substantial health benefits.http://www.sciencedirect.com/science/article/pii/S014765132201051XEnvironmental protection policyPM2.5ObesityObesity indicatorsChildren and adolescents |
| spellingShingle | Xiaohua Liang Fangchao Liu Fengchao Liang Yanling Ren Xian Tang Shunqing Luo Daochao Huang Wei Feng Association of decreases in PM2.5 levels due to the implementation of environmental protection policies with the incidence of obesity in adolescents: A prospective cohort study Ecotoxicology and Environmental Safety Environmental protection policy PM2.5 Obesity Obesity indicators Children and adolescents |
| title | Association of decreases in PM2.5 levels due to the implementation of environmental protection policies with the incidence of obesity in adolescents: A prospective cohort study |
| title_full | Association of decreases in PM2.5 levels due to the implementation of environmental protection policies with the incidence of obesity in adolescents: A prospective cohort study |
| title_fullStr | Association of decreases in PM2.5 levels due to the implementation of environmental protection policies with the incidence of obesity in adolescents: A prospective cohort study |
| title_full_unstemmed | Association of decreases in PM2.5 levels due to the implementation of environmental protection policies with the incidence of obesity in adolescents: A prospective cohort study |
| title_short | Association of decreases in PM2.5 levels due to the implementation of environmental protection policies with the incidence of obesity in adolescents: A prospective cohort study |
| title_sort | association of decreases in pm2 5 levels due to the implementation of environmental protection policies with the incidence of obesity in adolescents a prospective cohort study |
| topic | Environmental protection policy PM2.5 Obesity Obesity indicators Children and adolescents |
| url | http://www.sciencedirect.com/science/article/pii/S014765132201051X |
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