Comprehensive immunophenotyping of solid tumor-infiltrating immune cells reveals the expression characteristics of LAG-3 and its ligands

Comprehensive immunophenotyping of solid tumor-infiltrating immune cells reveals the expression characteristics of LAG-3 and its ligands

BackgroundImmune cell expression profiling from patient samples is critical for the successful development of immuno-oncology agents and is useful to understand mechanism-of-action, to identify exploratory biomarkers predictive of response, and to guide treatment selection and combination therapy st...

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Bibliographic Details
Main Authors: Bradley Garman, Can Jiang, Sherif Daouti, Sanah Kumar, Priyanka Mehta, Miye K. Jacques, Laurence Menard, Nataly Manjarrez-Orduno, Sonia Dolfi, Piali Mukherjee, Sharmila Chamling Rai, Ana Lako, Jennifer D. Koenitzer, Justin M. David
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
Immunophenotyping
Immunotherapy
TIL
LAG-3
PD-1
CD8 memory T cell
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1151748/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1151748/full

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