A convolutional neural network highlights mutations relevant to antimicrobial resistance in Mycobacterium tuberculosis

Pathogen whole genome sequencing, coupled with statistical and machine learning models, offers a promising solution to multi-drug resistance diagnosis. Here, the authors present two deep convolutional neural networks that predict the antibiotic resistance phenotypes of M. tuberculosis isolates.

Bibliographic Details
Main Authors: Anna G. Green, Chang Ho Yoon, Michael L. Chen, Yasha Ektefaie, Mack Fina, Luca Freschi, Matthias I. Gröschel, Isaac Kohane, Andrew Beam, Maha Farhat
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-31236-0