Protracted effects of juvenile stressor exposure are mitigated by access to palatable food.
Stressor experiences during the juvenile period may increase vulnerability to anxiety and depressive-like symptoms in adulthood. Stressors may also promote palatable feeding, possibly reflecting a form of self-medication. The current study investigated the short- and long-term consequences of a stre...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4011852?pdf=render |
| _version_ | 1818571464870199296 |
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| author | Jennifer Christine MacKay Jonathan Stewart James Christian Cayer Pamela Kent Hymie Anisman Zul Merali |
| author_facet | Jennifer Christine MacKay Jonathan Stewart James Christian Cayer Pamela Kent Hymie Anisman Zul Merali |
| author_sort | Jennifer Christine MacKay |
| collection | DOAJ |
| description | Stressor experiences during the juvenile period may increase vulnerability to anxiety and depressive-like symptoms in adulthood. Stressors may also promote palatable feeding, possibly reflecting a form of self-medication. The current study investigated the short- and long-term consequences of a stressor applied during the juvenile period on anxiety- and depressive-like behavior measured by the elevated plus maze (EPM), social interaction and forced swim test (FST). Furthermore, the effects of stress on caloric intake, preference for a palatable food and indices of metabolic syndrome and obesity were assessed. Male Wistar rats exposed to 3 consecutive days of variable stressors on postnatal days (PD) 27-29, displayed elevated anxiety-like behaviors as adults, which could be attenuated by consumption of a palatable high-fat diet. However, consumption of a palatable food in response to a stressor appeared to contribute to increased adiposity. |
| first_indexed | 2024-12-14T13:56:05Z |
| format | Article |
| id | doaj.art-324ecd0466fc4905997273a5fe6b041e |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-14T13:56:05Z |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-324ecd0466fc4905997273a5fe6b041e2022-12-21T22:58:50ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0195e9657310.1371/journal.pone.0096573Protracted effects of juvenile stressor exposure are mitigated by access to palatable food.Jennifer Christine MacKayJonathan Stewart JamesChristian CayerPamela KentHymie AnismanZul MeraliStressor experiences during the juvenile period may increase vulnerability to anxiety and depressive-like symptoms in adulthood. Stressors may also promote palatable feeding, possibly reflecting a form of self-medication. The current study investigated the short- and long-term consequences of a stressor applied during the juvenile period on anxiety- and depressive-like behavior measured by the elevated plus maze (EPM), social interaction and forced swim test (FST). Furthermore, the effects of stress on caloric intake, preference for a palatable food and indices of metabolic syndrome and obesity were assessed. Male Wistar rats exposed to 3 consecutive days of variable stressors on postnatal days (PD) 27-29, displayed elevated anxiety-like behaviors as adults, which could be attenuated by consumption of a palatable high-fat diet. However, consumption of a palatable food in response to a stressor appeared to contribute to increased adiposity.http://europepmc.org/articles/PMC4011852?pdf=render |
| spellingShingle | Jennifer Christine MacKay Jonathan Stewart James Christian Cayer Pamela Kent Hymie Anisman Zul Merali Protracted effects of juvenile stressor exposure are mitigated by access to palatable food. PLoS ONE |
| title | Protracted effects of juvenile stressor exposure are mitigated by access to palatable food. |
| title_full | Protracted effects of juvenile stressor exposure are mitigated by access to palatable food. |
| title_fullStr | Protracted effects of juvenile stressor exposure are mitigated by access to palatable food. |
| title_full_unstemmed | Protracted effects of juvenile stressor exposure are mitigated by access to palatable food. |
| title_short | Protracted effects of juvenile stressor exposure are mitigated by access to palatable food. |
| title_sort | protracted effects of juvenile stressor exposure are mitigated by access to palatable food |
| url | http://europepmc.org/articles/PMC4011852?pdf=render |
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