343 Development of osteoclast derived exosomes for vascular calcification therapy

343 Development of osteoclast derived exosomes for vascular calcification therapy

OBJECTIVES/GOALS: The global incidence of calcific aortic valve disease (CAVD) increased 3.5-fold since 1990. No preventative or therapeutic pharmaceutical therapies exist for CAVD. We will establish the therapeutic potential of osteoclast-derived exosomes though characterization of contents and mec...

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Bibliographic Details
Main Authors: Isabella Jennings, Hao Zhou, Suryo Kuncorojakti, Medania Purwaningrum, Marta Scatena, Cecilia M. Giachelli
Format: Article
Language:English
Published: Cambridge University Press 2024-04-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866124003054/type/journal_article

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