Overexpressed p-S6 associates with lymph node metastasis and predicts poor prognosis in non-small cell lung cancer

Overexpressed p-S6 associates with lymph node metastasis and predicts poor prognosis in non-small cell lung cancer

Abstract Background Ribosomal protein S6 (S6), a downstream effect media of the AKT/mTOR pathway, not only is a part of 40S small subunit of eukaryotic ribosome, but also involves in protein synthesis and cell proliferation during cancer development. Methods In present study, we explore the associat...

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Bibliographic Details
Main Authors: Yaoxiang Tang, Jiadi Luo, Ying Zhou, Hongjing Zang, Yang Yang, Sile Liu, Hongmei Zheng, Jian Ma, Songqing Fan, Qiuyuan Wen
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Cancer
Subjects:
P-S6
Lymph node metastasis
Prognosis
Non-small cell lung cancer
Online Access:https://doi.org/10.1186/s12885-022-09664-4

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