Prevention of sudden cardiac death beyond the ICD: Have we reached the boundary or are we just burning the surface?
Preventing sudden cardiac death (SCD) remains a major unsolved problem in contemporary medical practice. As the most common cause of SCD, treatment for ventricular arrhythmias is the target area of interest in research field. While implantable cardioverter-defibrillator (ICD) effectively decreases d...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2014-01-01
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| Series: | Indian Heart Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0019483213004422 |
| _version_ | 1819094572482953216 |
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| author | Niyada Naksuk Christopher V. DeSimone Suraj Kapa Samuel J. Asirvatham |
| author_facet | Niyada Naksuk Christopher V. DeSimone Suraj Kapa Samuel J. Asirvatham |
| author_sort | Niyada Naksuk |
| collection | DOAJ |
| description | Preventing sudden cardiac death (SCD) remains a major unsolved problem in contemporary medical practice. As the most common cause of SCD, treatment for ventricular arrhythmias is the target area of interest in research field. While implantable cardioverter-defibrillator (ICD) effectively decreases death from ventricular arrhythmias in highly selected patients, risk of inappropriate shocks, mortality from frequent therapy, chance of failing in abortion of arrhythmias despite having a defibrillator, and our inability to recognize which of several hundreds of thousands of patients at risk for sudden death but do not meet current criteria for defibrillator, limit ICD effectiveness. In this article, a brief review of mechanism leading to SCD, the existing evidence for a defibrillator and the lacunae in present guidelines for patients clearly at risk for sudden death but without proven benefit from a defibrillator are presented in Section I. Following this, interventional approaches, both catheter-based and general measures that may serve as adjuncts to a defibrillator in preventing this all too common catastrophic end event, are summarized in Section II. |
| first_indexed | 2024-12-21T23:29:32Z |
| format | Article |
| id | doaj.art-325599cac5404cbf9df0ba0d100aec47 |
| institution | Directory Open Access Journal |
| issn | 0019-4832 |
| language | English |
| last_indexed | 2024-12-21T23:29:32Z |
| publishDate | 2014-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Indian Heart Journal |
| spelling | doaj.art-325599cac5404cbf9df0ba0d100aec472022-12-21T18:46:31ZengElsevierIndian Heart Journal0019-48322014-01-0166S1S120S12810.1016/j.ihj.2013.12.046Prevention of sudden cardiac death beyond the ICD: Have we reached the boundary or are we just burning the surface?Niyada Naksuk0Christopher V. DeSimone1Suraj Kapa2Samuel J. Asirvatham3Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USADivision of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USADivision of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USADivision of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USAPreventing sudden cardiac death (SCD) remains a major unsolved problem in contemporary medical practice. As the most common cause of SCD, treatment for ventricular arrhythmias is the target area of interest in research field. While implantable cardioverter-defibrillator (ICD) effectively decreases death from ventricular arrhythmias in highly selected patients, risk of inappropriate shocks, mortality from frequent therapy, chance of failing in abortion of arrhythmias despite having a defibrillator, and our inability to recognize which of several hundreds of thousands of patients at risk for sudden death but do not meet current criteria for defibrillator, limit ICD effectiveness. In this article, a brief review of mechanism leading to SCD, the existing evidence for a defibrillator and the lacunae in present guidelines for patients clearly at risk for sudden death but without proven benefit from a defibrillator are presented in Section I. Following this, interventional approaches, both catheter-based and general measures that may serve as adjuncts to a defibrillator in preventing this all too common catastrophic end event, are summarized in Section II.http://www.sciencedirect.com/science/article/pii/S0019483213004422Sudden cardiac deathVentricular tachycardiaIntracardiac-cardioverter defibrillatorPreventionMapping |
| spellingShingle | Niyada Naksuk Christopher V. DeSimone Suraj Kapa Samuel J. Asirvatham Prevention of sudden cardiac death beyond the ICD: Have we reached the boundary or are we just burning the surface? Indian Heart Journal Sudden cardiac death Ventricular tachycardia Intracardiac-cardioverter defibrillator Prevention Mapping |
| title | Prevention of sudden cardiac death beyond the ICD: Have we reached the boundary or are we just burning the surface? |
| title_full | Prevention of sudden cardiac death beyond the ICD: Have we reached the boundary or are we just burning the surface? |
| title_fullStr | Prevention of sudden cardiac death beyond the ICD: Have we reached the boundary or are we just burning the surface? |
| title_full_unstemmed | Prevention of sudden cardiac death beyond the ICD: Have we reached the boundary or are we just burning the surface? |
| title_short | Prevention of sudden cardiac death beyond the ICD: Have we reached the boundary or are we just burning the surface? |
| title_sort | prevention of sudden cardiac death beyond the icd have we reached the boundary or are we just burning the surface |
| topic | Sudden cardiac death Ventricular tachycardia Intracardiac-cardioverter defibrillator Prevention Mapping |
| url | http://www.sciencedirect.com/science/article/pii/S0019483213004422 |
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