mTOR acts as a pivotal signaling hub for neural crest cells during craniofacial development.
mTOR is a highly conserved serine/threonine protein kinase that is critical for diverse cellular processes in both developmental and physiological settings. mTOR interacts with a set of molecules including Raptor and Rictor to form two distinct functional complexes, namely the mTORC1 and mTORC2. Her...
Main Authors: | Xuguang Nie, Jinxuan Zheng, Christopher L Ricupero, Ling He, Kai Jiao, Jeremy J Mao |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-07-01
|
Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC6049956?pdf=render |
Similar Items
-
The Role of RNA-Binding Proteins in Vertebrate Neural Crest and Craniofacial Development
by: Thomas E. Forman, et al.
Published: (2021-08-01) -
Genomic factors that shape craniofacial outcome and neural crest vulnerability in FASD
by: Susan M. Smith, et al.
Published: (2014-08-01) -
Cranial Neural Crest Cells and Their Role in the Pathogenesis of Craniofacial Anomalies and Coronal Craniosynostosis
by: Erica M. Siismets, et al.
Published: (2020-09-01) -
The Role of Sonic Hedgehog in Craniofacial Patterning, Morphogenesis and Cranial Neural Crest Survival
by: Sebastian Dworkin, et al.
Published: (2016-08-01) -
Snrpb is required in murine neural crest cells for proper splicing and craniofacial morphogenesis
by: Sabrina Shameen Alam, et al.
Published: (2022-06-01)