Current State of the Art and Next Generation of Materials for a Customized IntraOcular Lens according to a Patient-Specific Eye Power
Intraocular lenses (IOLs) are commonly implanted after surgical removal of a cataractous lens. A variety of IOL materials are currently available, including collamer, hydrophobic acrylic, hydrophilic acrylic, PHEMA copolymer, polymethylmethacrylate (PMMA), and silicone. High-quality polymers with di...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-03-01
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| Series: | Polymers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4360/15/6/1590 |
| _version_ | 1797609260818890752 |
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| author | Martina Vacalebre Renato Frison Carmelo Corsaro Fortunato Neri Antonio Santoro Sabrina Conoci Elena Anastasi Maria Cristina Curatolo Enza Fazio |
| author_facet | Martina Vacalebre Renato Frison Carmelo Corsaro Fortunato Neri Antonio Santoro Sabrina Conoci Elena Anastasi Maria Cristina Curatolo Enza Fazio |
| author_sort | Martina Vacalebre |
| collection | DOAJ |
| description | Intraocular lenses (IOLs) are commonly implanted after surgical removal of a cataractous lens. A variety of IOL materials are currently available, including collamer, hydrophobic acrylic, hydrophilic acrylic, PHEMA copolymer, polymethylmethacrylate (PMMA), and silicone. High-quality polymers with distinct physical and optical properties for IOL manufacturing and in line with the highest quality standards on the market have evolved to encompass medical needs. Each of them and their packaging show unique advantages and disadvantages. Here, we highlight the evolution of polymeric materials and mainly the current state of the art of the unique properties of some polymeric systems used for IOL design, identifying current limitations for future improvements. We investigate the characteristics of the next generation of IOL materials, which must satisfy biocompatibility requirements and have tuneable refractive index to create patient-specific eye power, preventing formation of posterior capsular opacification. |
| first_indexed | 2024-03-11T05:58:59Z |
| format | Article |
| id | doaj.art-325912a27ab3424288d55a45b69ef83a |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-03-11T05:58:59Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-325912a27ab3424288d55a45b69ef83a2023-11-17T13:27:40ZengMDPI AGPolymers2073-43602023-03-01156159010.3390/polym15061590Current State of the Art and Next Generation of Materials for a Customized IntraOcular Lens according to a Patient-Specific Eye PowerMartina Vacalebre0Renato Frison1Carmelo Corsaro2Fortunato Neri3Antonio Santoro4Sabrina Conoci5Elena Anastasi6Maria Cristina Curatolo7Enza Fazio8Dipartimento di Scienze Matematiche ed Informatiche, Scienze Fisiche e Scienze della Terra (MIFT), Università di Messina, V.le Ferdinando Stagno d’Alcontres 31, 98166 Messina, ItalyOptical Consultant SIFI SpA, 95025 Aci Sant’Antonio (CT), ItalyDipartimento di Scienze Matematiche ed Informatiche, Scienze Fisiche e Scienze della Terra (MIFT), Università di Messina, V.le Ferdinando Stagno d’Alcontres 31, 98166 Messina, ItalyDipartimento di Scienze Matematiche ed Informatiche, Scienze Fisiche e Scienze della Terra (MIFT), Università di Messina, V.le Ferdinando Stagno d’Alcontres 31, 98166 Messina, ItalyDipartimento di Scienze Chimiche, Biologiche, Farmacologiche ed Ambientali (CHIBIOFARAM), Università di Messina, V.le Ferdinando Stagno d’Alcontres 31, 98166 Messina, ItalyDipartimento di Scienze Chimiche, Biologiche, Farmacologiche ed Ambientali (CHIBIOFARAM), Università di Messina, V.le Ferdinando Stagno d’Alcontres 31, 98166 Messina, ItalyInnovation and Medical Science, SIFI SpA, 95025 Aci Sant’Antonio (CT), ItalyInnovation and Medical Science, SIFI SpA, 95025 Aci Sant’Antonio (CT), ItalyDipartimento di Scienze Matematiche ed Informatiche, Scienze Fisiche e Scienze della Terra (MIFT), Università di Messina, V.le Ferdinando Stagno d’Alcontres 31, 98166 Messina, ItalyIntraocular lenses (IOLs) are commonly implanted after surgical removal of a cataractous lens. A variety of IOL materials are currently available, including collamer, hydrophobic acrylic, hydrophilic acrylic, PHEMA copolymer, polymethylmethacrylate (PMMA), and silicone. High-quality polymers with distinct physical and optical properties for IOL manufacturing and in line with the highest quality standards on the market have evolved to encompass medical needs. Each of them and their packaging show unique advantages and disadvantages. Here, we highlight the evolution of polymeric materials and mainly the current state of the art of the unique properties of some polymeric systems used for IOL design, identifying current limitations for future improvements. We investigate the characteristics of the next generation of IOL materials, which must satisfy biocompatibility requirements and have tuneable refractive index to create patient-specific eye power, preventing formation of posterior capsular opacification.https://www.mdpi.com/2073-4360/15/6/1590intraocular lensGRadient INdex lensacrylic materialshydrogelhydrophobicityhydrophilicity |
| spellingShingle | Martina Vacalebre Renato Frison Carmelo Corsaro Fortunato Neri Antonio Santoro Sabrina Conoci Elena Anastasi Maria Cristina Curatolo Enza Fazio Current State of the Art and Next Generation of Materials for a Customized IntraOcular Lens according to a Patient-Specific Eye Power Polymers intraocular lens GRadient INdex lens acrylic materials hydrogel hydrophobicity hydrophilicity |
| title | Current State of the Art and Next Generation of Materials for a Customized IntraOcular Lens according to a Patient-Specific Eye Power |
| title_full | Current State of the Art and Next Generation of Materials for a Customized IntraOcular Lens according to a Patient-Specific Eye Power |
| title_fullStr | Current State of the Art and Next Generation of Materials for a Customized IntraOcular Lens according to a Patient-Specific Eye Power |
| title_full_unstemmed | Current State of the Art and Next Generation of Materials for a Customized IntraOcular Lens according to a Patient-Specific Eye Power |
| title_short | Current State of the Art and Next Generation of Materials for a Customized IntraOcular Lens according to a Patient-Specific Eye Power |
| title_sort | current state of the art and next generation of materials for a customized intraocular lens according to a patient specific eye power |
| topic | intraocular lens GRadient INdex lens acrylic materials hydrogel hydrophobicity hydrophilicity |
| url | https://www.mdpi.com/2073-4360/15/6/1590 |
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