Cerebral Malaria Is Regulated by Host-Mediated Changes in Plasmodium Gene Expression

Cerebral Malaria Is Regulated by Host-Mediated Changes in Plasmodium Gene Expression

ABSTRACT Cerebral malaria (CM), the deadliest complication of Plasmodium infection, is a complex and unpredictable disease. However, our understanding of the host and parasite factors that cause CM is limited. Using a mouse model of CM, experimental CM (ECM), we performed a three-way comparison betw...

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Bibliographic Details
Main Authors: Clare K. Cimperman, Mirna Pena, Sohret M. Gokcek, Brandon P. Theall, Meha V. Patel, Anisha Sharma, ChenFeng Qi, Daniel Sturdevant, Louis H. Miller, Patrick L. Collins, Susan K. Pierce, Munir Akkaya
Format: Article
Language:English
Published: American Society for Microbiology 2023-04-01
Series:mBio
Subjects:
Plasmodium
cell-mediated immunity
cerebral malaria
host-parasite relationship
malaria
Online Access:https://journals.asm.org/doi/10.1128/mbio.03391-22

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