Research progress on unique paratope structure, antigen binding modes, and systematic mutagenesis strategies of single-domain antibodies

Research progress on unique paratope structure, antigen binding modes, and systematic mutagenesis strategies of single-domain antibodies

Single-domain antibodies (sdAbs) showed the incredible advantages of small molecular weight, excellent affinity, specificity, and stability compared with traditional IgG antibodies, so their potential in binding hidden antigen epitopes and hazard detection in food, agricultural and veterinary fields...

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Bibliographic Details
Main Authors: Chang Liu, Hong Lin, Limin Cao, Kaiqiang Wang, Jianxin Sui
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
single-domain antibody
structure
binding modes
mutagenesis
epitope
paratope
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1059771/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1059771/full

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