Incidence of Pancreatic Fistula after Distal Pancreatectomy and Efficacy of Endoscopic Therapy for Its Management: Results from a Tertiary Care Center

Pancreatic fistula is a known complication of distal pancreatectomy. Endotherapy with pancreatic duct stent placement and pancreatic sphincterotomy has been shown to be effective in its management; however, experience of endotherapy in the management of this complication has not been extensively rep...

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Main Authors: Savio C. Reddymasu, Kavous Pakseresht, Brian Moloney, Benjamin Alsop, Melissa Oropezia-Vail, Mojtaba Olyaee
Format: Article
Language:English
Published: Karger Publishers 2013-08-01
Series:Case Reports in Gastroenterology
Subjects:
Online Access:http://www.karger.com/Article/FullText/354136
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author Savio C. Reddymasu
Kavous Pakseresht
Brian Moloney
Benjamin Alsop
Melissa Oropezia-Vail
Mojtaba Olyaee
author_facet Savio C. Reddymasu
Kavous Pakseresht
Brian Moloney
Benjamin Alsop
Melissa Oropezia-Vail
Mojtaba Olyaee
author_sort Savio C. Reddymasu
collection DOAJ
description Pancreatic fistula is a known complication of distal pancreatectomy. Endotherapy with pancreatic duct stent placement and pancreatic sphincterotomy has been shown to be effective in its management; however, experience of endotherapy in the management of this complication has not been extensively reported from the United States. Preoperative endoscopic retrograde cholangiopancreatography (ERCP) with pancreatic stent placement has also been proposed to prevent this complication after distal pancreatectomy. In our cohort of 59 patients who underwent distal pancreatectomy, 13 (22%) developed a pancreatic fistula in the immediate postoperative period, of whom 8 (14%) patients (5 female, mean age 52 years) were referred for an ERCP because of ongoing symptoms related to the pancreatic fistula. The pancreatic fistula resolved in all patients after a median duration of 62 days from the index ERCP. The median number of ERCPs required to document resolution of the pancreatic fistula was 2. Although a sizeable percentage of patients develop a pancreatic fistula after distal pancreatectomy, only a small percentage of patients require ERCP for management of this complication. Given the high success rate of endotherapy in resolving pancreatic fistula and the fact that the majority of patients who undergo distal pancreatectomy never require an ERCP, performing ERCP for prophylactic pancreatic duct stent prior to distal pancreatectomy might not be necessary.
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spelling doaj.art-326ac8a20f0a4d43a0b34d5e979ff50f2022-12-22T02:50:03ZengKarger PublishersCase Reports in Gastroenterology1662-06312013-08-017233233910.1159/000354136354136Incidence of Pancreatic Fistula after Distal Pancreatectomy and Efficacy of Endoscopic Therapy for Its Management: Results from a Tertiary Care CenterSavio C. ReddymasuKavous PaksereshtBrian MoloneyBenjamin AlsopMelissa Oropezia-VailMojtaba OlyaeePancreatic fistula is a known complication of distal pancreatectomy. Endotherapy with pancreatic duct stent placement and pancreatic sphincterotomy has been shown to be effective in its management; however, experience of endotherapy in the management of this complication has not been extensively reported from the United States. Preoperative endoscopic retrograde cholangiopancreatography (ERCP) with pancreatic stent placement has also been proposed to prevent this complication after distal pancreatectomy. In our cohort of 59 patients who underwent distal pancreatectomy, 13 (22%) developed a pancreatic fistula in the immediate postoperative period, of whom 8 (14%) patients (5 female, mean age 52 years) were referred for an ERCP because of ongoing symptoms related to the pancreatic fistula. The pancreatic fistula resolved in all patients after a median duration of 62 days from the index ERCP. The median number of ERCPs required to document resolution of the pancreatic fistula was 2. Although a sizeable percentage of patients develop a pancreatic fistula after distal pancreatectomy, only a small percentage of patients require ERCP for management of this complication. Given the high success rate of endotherapy in resolving pancreatic fistula and the fact that the majority of patients who undergo distal pancreatectomy never require an ERCP, performing ERCP for prophylactic pancreatic duct stent prior to distal pancreatectomy might not be necessary.http://www.karger.com/Article/FullText/354136Distal pancreatectomyPancreatic fistulaPancreatic leakPancreatic duct stenting
spellingShingle Savio C. Reddymasu
Kavous Pakseresht
Brian Moloney
Benjamin Alsop
Melissa Oropezia-Vail
Mojtaba Olyaee
Incidence of Pancreatic Fistula after Distal Pancreatectomy and Efficacy of Endoscopic Therapy for Its Management: Results from a Tertiary Care Center
Case Reports in Gastroenterology
Distal pancreatectomy
Pancreatic fistula
Pancreatic leak
Pancreatic duct stenting
title Incidence of Pancreatic Fistula after Distal Pancreatectomy and Efficacy of Endoscopic Therapy for Its Management: Results from a Tertiary Care Center
title_full Incidence of Pancreatic Fistula after Distal Pancreatectomy and Efficacy of Endoscopic Therapy for Its Management: Results from a Tertiary Care Center
title_fullStr Incidence of Pancreatic Fistula after Distal Pancreatectomy and Efficacy of Endoscopic Therapy for Its Management: Results from a Tertiary Care Center
title_full_unstemmed Incidence of Pancreatic Fistula after Distal Pancreatectomy and Efficacy of Endoscopic Therapy for Its Management: Results from a Tertiary Care Center
title_short Incidence of Pancreatic Fistula after Distal Pancreatectomy and Efficacy of Endoscopic Therapy for Its Management: Results from a Tertiary Care Center
title_sort incidence of pancreatic fistula after distal pancreatectomy and efficacy of endoscopic therapy for its management results from a tertiary care center
topic Distal pancreatectomy
Pancreatic fistula
Pancreatic leak
Pancreatic duct stenting
url http://www.karger.com/Article/FullText/354136
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