Insights into the function of HDAC3 and NCoR1/NCoR2 co-repressor complex in metabolic diseases

Insights into the function of HDAC3 and NCoR1/NCoR2 co-repressor complex in metabolic diseases

Histone deacetylase 3 (HDAC3) and nuclear receptor co-repressor (NCoR1/2) are epigenetic regulators that play a key role in gene expression and metabolism. HDAC3 is a class I histone deacetylase that functions as a transcriptional co-repressor, modulating gene expression by removing acetyl groups fr...

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Bibliographic Details
Main Authors: Harikrishnareddy Paluvai, Kumar D. Shanmukha, Jens Tyedmers, Johannes Backs
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Molecular Biosciences
Subjects:
HDAC3
NCoR1
SMRT
GPS2
PPARs
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1190094/full

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