Evaluating purifying selection in the mitochondrial DNA of various mammalian species.

Evaluating purifying selection in the mitochondrial DNA of various mammalian species.

Mitochondrial DNA (mtDNA), the circular DNA molecule inside the mitochondria of all eukaryotic cells, has been shown to be under the effect of purifying selection in several species. Traditional testing of purifying selection has been based simply on ratios of nonsynonymous to synonymous mutations,...

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Bibliographic Details
Main Authors:	Pedro Soares, Diogo Abrantes, Teresa Rito, Noel Thomson, Predrag Radivojac, Biao Li, Vincent Macaulay, David C Samuels, Luísa Pereira
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2013-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3606437?pdf=render

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