Pediatric functional dyspepsia: A comprehensive review
Functional dyspepsia (FD) is a common but heterogeneous upper gastrointestinal disorder that causes recurrent and/or chronic epigastric symptoms, with an estimated prevalence in children between 3% and 27%. Etiologies include genetic predisposition and events that cause disruption of the brain-gut-m...
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| Format: | Article |
| Language: | English |
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Permanyer
2021-07-01
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| Series: | Neurogastro LATAM Reviews |
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| Online Access: | https://www.neurogastrolatamreviews.com/frame_esp.php?id=123 |
| _version_ | 1811191202380251136 |
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| author | Liz Febo-Rodríguez |
| author_facet | Liz Febo-Rodríguez |
| author_sort | Liz Febo-Rodríguez |
| collection | DOAJ |
| description | Functional dyspepsia (FD) is a common but heterogeneous upper gastrointestinal disorder that causes recurrent and/or chronic epigastric symptoms, with an estimated prevalence in children between 3% and 27%. Etiologies include genetic predisposition and events that cause disruption of the brain-gut-microbiota axis, such as environmental and psychosocial stressors, disturbance of the gut microbiota, and early life events that lead to hyperalgesia such as cow’s milk protein. FD results in impaired quality of life and increased health care costs, with an estimated $5 billion in annual costs. Unfortunately, treatment options are limited given the complexity of its pathophysiology and the fact that most therapies are studied in adults and not children, thus making FD difficult to manage in pediatrics. |
| first_indexed | 2024-04-11T15:01:27Z |
| format | Article |
| id | doaj.art-3271b963b6b04c69b1bfe709e43f6894 |
| institution | Directory Open Access Journal |
| issn | 2462-7011 |
| language | English |
| last_indexed | 2024-04-11T15:01:27Z |
| publishDate | 2021-07-01 |
| publisher | Permanyer |
| record_format | Article |
| series | Neurogastro LATAM Reviews |
| spelling | doaj.art-3271b963b6b04c69b1bfe709e43f68942022-12-22T04:16:56ZengPermanyerNeurogastro LATAM Reviews2462-70112021-07-015310.24875/NGL.21000013Pediatric functional dyspepsia: A comprehensive reviewLiz Febo-Rodríguez0Department of Pediatric Gastroenterology, Hepatology, and Nutrition, University of Miami, Miami, Florida, United StatesFunctional dyspepsia (FD) is a common but heterogeneous upper gastrointestinal disorder that causes recurrent and/or chronic epigastric symptoms, with an estimated prevalence in children between 3% and 27%. Etiologies include genetic predisposition and events that cause disruption of the brain-gut-microbiota axis, such as environmental and psychosocial stressors, disturbance of the gut microbiota, and early life events that lead to hyperalgesia such as cow’s milk protein. FD results in impaired quality of life and increased health care costs, with an estimated $5 billion in annual costs. Unfortunately, treatment options are limited given the complexity of its pathophysiology and the fact that most therapies are studied in adults and not children, thus making FD difficult to manage in pediatrics.https://www.neurogastrolatamreviews.com/frame_esp.php?id=123Functional dyspepsia. Pediatric abdominal pain. Motility. Microbiome. Pharmacology. |
| spellingShingle | Liz Febo-Rodríguez Pediatric functional dyspepsia: A comprehensive review Neurogastro LATAM Reviews Functional dyspepsia. Pediatric abdominal pain. Motility. Microbiome. Pharmacology. |
| title | Pediatric functional dyspepsia: A comprehensive review |
| title_full | Pediatric functional dyspepsia: A comprehensive review |
| title_fullStr | Pediatric functional dyspepsia: A comprehensive review |
| title_full_unstemmed | Pediatric functional dyspepsia: A comprehensive review |
| title_short | Pediatric functional dyspepsia: A comprehensive review |
| title_sort | pediatric functional dyspepsia a comprehensive review |
| topic | Functional dyspepsia. Pediatric abdominal pain. Motility. Microbiome. Pharmacology. |
| url | https://www.neurogastrolatamreviews.com/frame_esp.php?id=123 |
| work_keys_str_mv | AT lizfeborodriguez pediatricfunctionaldyspepsiaacomprehensivereview |