Nanotechnology-Based Strategies to Combat Multidrug-Resistant <i>Candida auris</i> Infections
An emerging multidrug-resistant pathogenic yeast called <i>Candida auris</i> has a high potential to spread quickly among hospitalized patients and immunodeficient patients causing nosocomial outbreaks. It has the potential to cause pandemic outbreaks in about 45 nations with high mortal...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Pathogens |
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| Online Access: | https://www.mdpi.com/2076-0817/12/8/1033 |
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| author | Helal F. Hetta Yasmin N. Ramadan Israa M. S. Al-Kadmy Noura H. Abd Ellah Lama Shbibe Basem Battah |
| author_facet | Helal F. Hetta Yasmin N. Ramadan Israa M. S. Al-Kadmy Noura H. Abd Ellah Lama Shbibe Basem Battah |
| author_sort | Helal F. Hetta |
| collection | DOAJ |
| description | An emerging multidrug-resistant pathogenic yeast called <i>Candida auris</i> has a high potential to spread quickly among hospitalized patients and immunodeficient patients causing nosocomial outbreaks. It has the potential to cause pandemic outbreaks in about 45 nations with high mortality rates. Additionally, the fungus has become resistant to decontamination techniques and can survive for weeks in a hospital environment. Nanoparticles might be a good substitute to treat illnesses brought on by this newly discovered pathogen. Nanoparticles have become a trend and hot topic in recent years to combat this fatal fungus. This review gives a general insight into the epidemiology of <i>C. auris</i> and infection. It discusses the current conventional therapy and mechanism of resistance development. Furthermore, it focuses on nanoparticles, their different types, and up-to-date trials to evaluate the promising efficacy of nanoparticles with respect to <i>C. auris</i>. |
| first_indexed | 2024-03-10T23:40:21Z |
| format | Article |
| id | doaj.art-327486472b0643869f5d9add0a840371 |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-10T23:40:21Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-327486472b0643869f5d9add0a8403712023-11-19T02:32:34ZengMDPI AGPathogens2076-08172023-08-01128103310.3390/pathogens12081033Nanotechnology-Based Strategies to Combat Multidrug-Resistant <i>Candida auris</i> InfectionsHelal F. Hetta0Yasmin N. Ramadan1Israa M. S. Al-Kadmy2Noura H. Abd Ellah3Lama Shbibe4Basem Battah5Department of Medical Microbiology and Immunology, Faculty of Medicine, Assiut University, Assiut 71515, EgyptDepartment of Microbiology and Immunology, Faculty of Pharmacy, Assiut University, Assiut 71515, EgyptBranch of Biotechnology, Department of Biology, College of Science, Mustansiriyah University, Baghdad P.O. Box 10244, IraqDepartment of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut 71515, EgyptFaculty of Science, Damascus University, Damascus 97009, SyriaDepartment of Biochemistry and Microbiology, Faculty of Pharmacy, Syrian Private University (SPU), Daraa International Highway, Damascus 36822, SyriaAn emerging multidrug-resistant pathogenic yeast called <i>Candida auris</i> has a high potential to spread quickly among hospitalized patients and immunodeficient patients causing nosocomial outbreaks. It has the potential to cause pandemic outbreaks in about 45 nations with high mortality rates. Additionally, the fungus has become resistant to decontamination techniques and can survive for weeks in a hospital environment. Nanoparticles might be a good substitute to treat illnesses brought on by this newly discovered pathogen. Nanoparticles have become a trend and hot topic in recent years to combat this fatal fungus. This review gives a general insight into the epidemiology of <i>C. auris</i> and infection. It discusses the current conventional therapy and mechanism of resistance development. Furthermore, it focuses on nanoparticles, their different types, and up-to-date trials to evaluate the promising efficacy of nanoparticles with respect to <i>C. auris</i>.https://www.mdpi.com/2076-0817/12/8/1033nanotechnology<i>Candida auris</i>MDRantifungal resistance |
| spellingShingle | Helal F. Hetta Yasmin N. Ramadan Israa M. S. Al-Kadmy Noura H. Abd Ellah Lama Shbibe Basem Battah Nanotechnology-Based Strategies to Combat Multidrug-Resistant <i>Candida auris</i> Infections Pathogens nanotechnology <i>Candida auris</i> MDR antifungal resistance |
| title | Nanotechnology-Based Strategies to Combat Multidrug-Resistant <i>Candida auris</i> Infections |
| title_full | Nanotechnology-Based Strategies to Combat Multidrug-Resistant <i>Candida auris</i> Infections |
| title_fullStr | Nanotechnology-Based Strategies to Combat Multidrug-Resistant <i>Candida auris</i> Infections |
| title_full_unstemmed | Nanotechnology-Based Strategies to Combat Multidrug-Resistant <i>Candida auris</i> Infections |
| title_short | Nanotechnology-Based Strategies to Combat Multidrug-Resistant <i>Candida auris</i> Infections |
| title_sort | nanotechnology based strategies to combat multidrug resistant i candida auris i infections |
| topic | nanotechnology <i>Candida auris</i> MDR antifungal resistance |
| url | https://www.mdpi.com/2076-0817/12/8/1033 |
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