Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercury
The frequencies of micronuclei (MN) and morphological nuclear abnormalities (NA) in erythrocytes in the peripheral blood of tambaqui (Colossoma macropomum), treated with 2 mg.L-1 methylmercury (MeHg), were analyzed. Two groups (nine specimens in each) were exposed to MeHg for different periods (grou...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Genética
2011-01-01
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| Series: | Genetics and Molecular Biology |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000400024 |
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| author | Carlos Alberto Machado da Rocha Lorena Araújo da Cunha Raul Henrique da Silva Pinheiro Marcelo de Oliveira Bahia Rommel Mario Rodríguez Burbano |
| author_facet | Carlos Alberto Machado da Rocha Lorena Araújo da Cunha Raul Henrique da Silva Pinheiro Marcelo de Oliveira Bahia Rommel Mario Rodríguez Burbano |
| author_sort | Carlos Alberto Machado da Rocha |
| collection | DOAJ |
| description | The frequencies of micronuclei (MN) and morphological nuclear abnormalities (NA) in erythrocytes in the peripheral blood of tambaqui (Colossoma macropomum), treated with 2 mg.L-1 methylmercury (MeHg), were analyzed. Two groups (nine specimens in each) were exposed to MeHg for different periods (group A - 24 h; group B - 120 h). A third group served as negative control (group C, untreated; n = 9). Although, when compared to the control group there were no significant differences in MN frequency in the treated groups, for NA, the differences between the frequencies of group B (treated for 120 h) and the control group were extremely significant (p < 0.02), thus demonstrating the potentially adverse effects of MeHg on C. macropomum erythrocytes after prolonged exposure. |
| first_indexed | 2024-12-11T19:42:41Z |
| format | Article |
| id | doaj.art-3274a020cb28492a9d3f86af55b50724 |
| institution | Directory Open Access Journal |
| issn | 1415-4757 1678-4685 |
| language | English |
| last_indexed | 2024-12-11T19:42:41Z |
| publishDate | 2011-01-01 |
| publisher | Sociedade Brasileira de Genética |
| record_format | Article |
| series | Genetics and Molecular Biology |
| spelling | doaj.art-3274a020cb28492a9d3f86af55b507242022-12-22T00:52:59ZengSociedade Brasileira de GenéticaGenetics and Molecular Biology1415-47571678-46852011-01-0134469469710.1590/S1415-47572011000400024Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercuryCarlos Alberto Machado da RochaLorena Araújo da CunhaRaul Henrique da Silva PinheiroMarcelo de Oliveira BahiaRommel Mario Rodríguez BurbanoThe frequencies of micronuclei (MN) and morphological nuclear abnormalities (NA) in erythrocytes in the peripheral blood of tambaqui (Colossoma macropomum), treated with 2 mg.L-1 methylmercury (MeHg), were analyzed. Two groups (nine specimens in each) were exposed to MeHg for different periods (group A - 24 h; group B - 120 h). A third group served as negative control (group C, untreated; n = 9). Although, when compared to the control group there were no significant differences in MN frequency in the treated groups, for NA, the differences between the frequencies of group B (treated for 120 h) and the control group were extremely significant (p < 0.02), thus demonstrating the potentially adverse effects of MeHg on C. macropomum erythrocytes after prolonged exposure.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000400024cytotoxicitygenotoxicitymethylmercurymicronuclei assay |
| spellingShingle | Carlos Alberto Machado da Rocha Lorena Araújo da Cunha Raul Henrique da Silva Pinheiro Marcelo de Oliveira Bahia Rommel Mario Rodríguez Burbano Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercury Genetics and Molecular Biology cytotoxicity genotoxicity methylmercury micronuclei assay |
| title | Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercury |
| title_full | Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercury |
| title_fullStr | Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercury |
| title_full_unstemmed | Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercury |
| title_short | Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercury |
| title_sort | studies of micronuclei and other nuclear abnormalities in red blood cells of colossoma macropomum exposed to methylmercury |
| topic | cytotoxicity genotoxicity methylmercury micronuclei assay |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000400024 |
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