D-Dimer Levels and Disease Prognosis in COVID-19 Patients
Elevated or abnormal levels of coagulation parameters indicate thrombotic disorders that need to be managed at the earliest to prevent complications and reduce mortality in coronavirus disease (COVID-19) patients. D-dimer is a product that is a part of fibrin abasement, which can be used as a test f...
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| Format: | Article |
| Language: | English |
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Journal of Pure and Applied Microbiology
2021-06-01
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| Series: | Journal of Pure and Applied Microbiology |
| Subjects: | |
| Online Access: | https://microbiologyjournal.org/d-dimer-levels-and-disease-prognosis-in-covid-19-patients/ |
| _version_ | 1819137189094621184 |
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| author | Manisha Khandait Ishi Sharma Rakesh Pandit |
| author_facet | Manisha Khandait Ishi Sharma Rakesh Pandit |
| author_sort | Manisha Khandait |
| collection | DOAJ |
| description | Elevated or abnormal levels of coagulation parameters indicate thrombotic disorders that need to be managed at the earliest to prevent complications and reduce mortality in coronavirus disease (COVID-19) patients. D-dimer is a product that is a part of fibrin abasement, which can be used as a test for the diagnosis of thrombotic disorders. Higher D-dimer levels are a strong indicator of mortality in patients with active COVID-19. This study aimed to determine the relationship between D-dimer levels and the clinical prognosis of COVID-19 patients. This observational, prospective study was conducted between April 2020 and September 2020. All patients with COVID-19 infection were considered for this study, along with their D-dimer values. Patients with higher D-dimer levels and pre-existing morbidities experienced a longer hospital stay and increased complications when compared to patients without pre-existing morbidities. Abnormally elevated D-dimer levels were frequently observed upon admission due to COVID-19 and are analogous to the increased occurrence of critical illness, thrombotic events, acute kidney injury, and death. Therefore, D-dimer levels could be a valuable clinical biomarker and an important indicator of prognosis for patients with COVID-19 with pre-existing morbidities. |
| first_indexed | 2024-12-22T10:46:55Z |
| format | Article |
| id | doaj.art-32753ed5d9294b5da3e4464507c58dab |
| institution | Directory Open Access Journal |
| issn | 0973-7510 2581-690X |
| language | English |
| last_indexed | 2024-12-22T10:46:55Z |
| publishDate | 2021-06-01 |
| publisher | Journal of Pure and Applied Microbiology |
| record_format | Article |
| series | Journal of Pure and Applied Microbiology |
| spelling | doaj.art-32753ed5d9294b5da3e4464507c58dab2022-12-21T18:28:54ZengJournal of Pure and Applied MicrobiologyJournal of Pure and Applied Microbiology0973-75102581-690X2021-06-0115281982510.22207/JPAM.15.2.36D-Dimer Levels and Disease Prognosis in COVID-19 PatientsManisha Khandaithttps://orcid.org/0000-0003-4441-1656Ishi Sharmahttps://orcid.org/0000-0001-6096-2840Rakesh Pandithttps://orcid.org/0000-0002-6822-1059Elevated or abnormal levels of coagulation parameters indicate thrombotic disorders that need to be managed at the earliest to prevent complications and reduce mortality in coronavirus disease (COVID-19) patients. D-dimer is a product that is a part of fibrin abasement, which can be used as a test for the diagnosis of thrombotic disorders. Higher D-dimer levels are a strong indicator of mortality in patients with active COVID-19. This study aimed to determine the relationship between D-dimer levels and the clinical prognosis of COVID-19 patients. This observational, prospective study was conducted between April 2020 and September 2020. All patients with COVID-19 infection were considered for this study, along with their D-dimer values. Patients with higher D-dimer levels and pre-existing morbidities experienced a longer hospital stay and increased complications when compared to patients without pre-existing morbidities. Abnormally elevated D-dimer levels were frequently observed upon admission due to COVID-19 and are analogous to the increased occurrence of critical illness, thrombotic events, acute kidney injury, and death. Therefore, D-dimer levels could be a valuable clinical biomarker and an important indicator of prognosis for patients with COVID-19 with pre-existing morbidities.https://microbiologyjournal.org/d-dimer-levels-and-disease-prognosis-in-covid-19-patients/covid-19coronavirusd-dimerhypercoagulationprognosismortality |
| spellingShingle | Manisha Khandait Ishi Sharma Rakesh Pandit D-Dimer Levels and Disease Prognosis in COVID-19 Patients Journal of Pure and Applied Microbiology covid-19 coronavirus d-dimer hypercoagulation prognosis mortality |
| title | D-Dimer Levels and Disease Prognosis in COVID-19 Patients |
| title_full | D-Dimer Levels and Disease Prognosis in COVID-19 Patients |
| title_fullStr | D-Dimer Levels and Disease Prognosis in COVID-19 Patients |
| title_full_unstemmed | D-Dimer Levels and Disease Prognosis in COVID-19 Patients |
| title_short | D-Dimer Levels and Disease Prognosis in COVID-19 Patients |
| title_sort | d dimer levels and disease prognosis in covid 19 patients |
| topic | covid-19 coronavirus d-dimer hypercoagulation prognosis mortality |
| url | https://microbiologyjournal.org/d-dimer-levels-and-disease-prognosis-in-covid-19-patients/ |
| work_keys_str_mv | AT manishakhandait ddimerlevelsanddiseaseprognosisincovid19patients AT ishisharma ddimerlevelsanddiseaseprognosisincovid19patients AT rakeshpandit ddimerlevelsanddiseaseprognosisincovid19patients |