<i>Rosmarinus officinalis</i> and Skin: Antioxidant Activity and Possible Therapeutical Role in Cutaneous Diseases
The rosemary plant, Rosmarinus officinalis L., one of the main members of the Lamiaceae family, is currently one of the most promising herbal medicines due to its pharmaceutical properties. This research aimed to evaluate the antioxidant role of Rosmarinus officinalis and its bioactive compounds on...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-03-01
|
| Series: | Antioxidants |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-3921/12/3/680 |
| _version_ | 1827751592824143872 |
|---|---|
| author | Federica Li Pomi Vincenzo Papa Francesco Borgia Mario Vaccaro Alessandro Allegra Nicola Cicero Sebastiano Gangemi |
| author_facet | Federica Li Pomi Vincenzo Papa Francesco Borgia Mario Vaccaro Alessandro Allegra Nicola Cicero Sebastiano Gangemi |
| author_sort | Federica Li Pomi |
| collection | DOAJ |
| description | The rosemary plant, Rosmarinus officinalis L., one of the main members of the Lamiaceae family, is currently one of the most promising herbal medicines due to its pharmaceutical properties. This research aimed to evaluate the antioxidant role of Rosmarinus officinalis and its bioactive compounds on the skin, with a focus on the newly emerging molecular mechanisms involved, providing extensive scientific evidence of its anti-inflammatory, antimicrobial, wound-healing and anticancer activity in dermatological practice. The search was conducted on articles concerning in vitro and in vivo studies in both animals and humans. The results obtained confirm the antioxidant role of R. officinalis. This assumption derives the possibility of using R. officinalis or its bioactive elements for the treatment of inflammatory and infectious skin pathologies. However, although the use of rosemary in the treatment of skin diseases represents a fascinating line of research, future perspectives still require large and controlled clinical trials in order to definitively elucidate the real impact of this plant and its components in clinical practice. |
| first_indexed | 2024-03-11T07:00:20Z |
| format | Article |
| id | doaj.art-3275df6cf43b44e6aebd8325317482cd |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-03-11T07:00:20Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-3275df6cf43b44e6aebd8325317482cd2023-11-17T09:18:15ZengMDPI AGAntioxidants2076-39212023-03-0112368010.3390/antiox12030680<i>Rosmarinus officinalis</i> and Skin: Antioxidant Activity and Possible Therapeutical Role in Cutaneous DiseasesFederica Li Pomi0Vincenzo Papa1Francesco Borgia2Mario Vaccaro3Alessandro Allegra4Nicola Cicero5Sebastiano Gangemi6Department of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, 98125 Messina, ItalyDepartment of Clinical and Experimental Medicine, School and Operative Unit of Allergy and Clinical Immunology, University of Messina, 98125 Messina, ItalyDepartment of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, 98125 Messina, ItalyDepartment of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, 98125 Messina, ItalyDivision of Haematology, Department of Human Pathology in Adulthood and Childhood “Gaetano Barresi”, University of Messina, 98125 Messina, ItalyDepartement of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, 98168 Messina, ItalyDepartment of Clinical and Experimental Medicine, School and Operative Unit of Allergy and Clinical Immunology, University of Messina, 98125 Messina, ItalyThe rosemary plant, Rosmarinus officinalis L., one of the main members of the Lamiaceae family, is currently one of the most promising herbal medicines due to its pharmaceutical properties. This research aimed to evaluate the antioxidant role of Rosmarinus officinalis and its bioactive compounds on the skin, with a focus on the newly emerging molecular mechanisms involved, providing extensive scientific evidence of its anti-inflammatory, antimicrobial, wound-healing and anticancer activity in dermatological practice. The search was conducted on articles concerning in vitro and in vivo studies in both animals and humans. The results obtained confirm the antioxidant role of R. officinalis. This assumption derives the possibility of using R. officinalis or its bioactive elements for the treatment of inflammatory and infectious skin pathologies. However, although the use of rosemary in the treatment of skin diseases represents a fascinating line of research, future perspectives still require large and controlled clinical trials in order to definitively elucidate the real impact of this plant and its components in clinical practice.https://www.mdpi.com/2076-3921/12/3/680<i>Rosmarinus officinalis</i>rosemaryskincutaneous diseaseoxidative stressROS |
| spellingShingle | Federica Li Pomi Vincenzo Papa Francesco Borgia Mario Vaccaro Alessandro Allegra Nicola Cicero Sebastiano Gangemi <i>Rosmarinus officinalis</i> and Skin: Antioxidant Activity and Possible Therapeutical Role in Cutaneous Diseases Antioxidants <i>Rosmarinus officinalis</i> rosemary skin cutaneous disease oxidative stress ROS |
| title | <i>Rosmarinus officinalis</i> and Skin: Antioxidant Activity and Possible Therapeutical Role in Cutaneous Diseases |
| title_full | <i>Rosmarinus officinalis</i> and Skin: Antioxidant Activity and Possible Therapeutical Role in Cutaneous Diseases |
| title_fullStr | <i>Rosmarinus officinalis</i> and Skin: Antioxidant Activity and Possible Therapeutical Role in Cutaneous Diseases |
| title_full_unstemmed | <i>Rosmarinus officinalis</i> and Skin: Antioxidant Activity and Possible Therapeutical Role in Cutaneous Diseases |
| title_short | <i>Rosmarinus officinalis</i> and Skin: Antioxidant Activity and Possible Therapeutical Role in Cutaneous Diseases |
| title_sort | i rosmarinus officinalis i and skin antioxidant activity and possible therapeutical role in cutaneous diseases |
| topic | <i>Rosmarinus officinalis</i> rosemary skin cutaneous disease oxidative stress ROS |
| url | https://www.mdpi.com/2076-3921/12/3/680 |
| work_keys_str_mv | AT federicalipomi irosmarinusofficinalisiandskinantioxidantactivityandpossibletherapeuticalroleincutaneousdiseases AT vincenzopapa irosmarinusofficinalisiandskinantioxidantactivityandpossibletherapeuticalroleincutaneousdiseases AT francescoborgia irosmarinusofficinalisiandskinantioxidantactivityandpossibletherapeuticalroleincutaneousdiseases AT mariovaccaro irosmarinusofficinalisiandskinantioxidantactivityandpossibletherapeuticalroleincutaneousdiseases AT alessandroallegra irosmarinusofficinalisiandskinantioxidantactivityandpossibletherapeuticalroleincutaneousdiseases AT nicolacicero irosmarinusofficinalisiandskinantioxidantactivityandpossibletherapeuticalroleincutaneousdiseases AT sebastianogangemi irosmarinusofficinalisiandskinantioxidantactivityandpossibletherapeuticalroleincutaneousdiseases |