Spatial maps of hepatocellular carcinoma transcriptomes highlight an unexplored landscape of heterogeneity and a novel gene signature for survival

Spatial maps of hepatocellular carcinoma transcriptomes highlight an unexplored landscape of heterogeneity and a novel gene signature for survival

Abstract Background Hepatocellular carcinoma (HCC) often presents with satellite nodules, rendering current curative treatments ineffective in many patients. The heterogeneity of HCC is a major challenge in personalized medicine. The emergence of spatial transcriptomics (ST) provides a powerful stra...

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Bibliographic Details
Main Authors: Nan Zhao, Yanhui Zhang, Runfen Cheng, Danfang Zhang, Fan Li, Yuhong Guo, Zhiqiang Qiu, Xueyi Dong, Xinchao Ban, Baocun Sun, Xiulan Zhao
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Cancer Cell International
Subjects:
Hepatocellular carcinoma (HCC)
Heterogeneity
Spatial transcriptomics (ST)
Satellite nodules
Gene signature
Online Access:https://doi.org/10.1186/s12935-021-02430-9

Internet

https://doi.org/10.1186/s12935-021-02430-9

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