Inflammation-associated DNA methylation patterns in epithelium of ulcerative colitis

Inflammation-associated DNA methylation patterns in epithelium of ulcerative colitis

Aberrant DNA methylation patterns have been reported in inflamed tissues and may play a role in disease. We studied DNA methylation and gene expression profiles of purified intestinal epithelial cells from ulcerative colitis patients, comparing inflamed and non-inflamed areas of the colon. We identi...

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Bibliographic Details
Main Authors: Alan Barnicle, Cathal Seoighe, John M. Greally, Aaron Golden, Laurence J. Egan
Format: Article
Language:English
Published: Taylor & Francis Group 2017-08-01
Series:Epigenetics
Subjects:
dna methylation
intestinal epithelial cell
inflammatory bowel disease
transcriptome
ulcerative colitis
Online Access:http://dx.doi.org/10.1080/15592294.2017.1334023

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