Analytical Insights into Protein–Alum Interactions and Their Impact on Conformational Epitope

Analytical Insights into Protein–Alum Interactions and Their Impact on Conformational Epitope

Several alum-adjuvanted vaccines have been licensed in the past 40 years. Despite its extensive and continuous use, the immune mechanism of action of alum adjuvants is not yet completely understood. Many different variables during the formulation process have been assessed as critical for alum-adjuv...

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Bibliographic Details
Main Authors: Alessio Corrado, Mila Toppazzini, Alessandro Vadi, Carmine Malzone, Rosy Galasso, Alessandro Donati, Riccardo De Ricco, Francesco Berti
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Pharmaceutics
Subjects:
bacterial vaccines
adjuvant
protein subunit
vesicles
meningococcal
Online Access:https://www.mdpi.com/1999-4923/16/3/420

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