Semi-Supervised Auto-Encoder Graph Network for Diabetic Retinopathy Grading

Diabetic Retinopathy (DR) causes quite a few blindness worldwide, which can be refrained by the timely diagnosis on retinal images. Recently, researches on deep learning-based retinal image classification have accelerated outstanding improvements in DR grading task. However, existing DR grading work...

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Main Authors: Yujie Li, Zhang Song, Sunkyoung Kang, Sungtae Jung, Wenpei Kang
Format: Article
Language:English
Published: IEEE 2021-01-01
Series:IEEE Access
Subjects:
Online Access:https://ieeexplore.ieee.org/document/9567704/
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author Yujie Li
Zhang Song
Sunkyoung Kang
Sungtae Jung
Wenpei Kang
author_facet Yujie Li
Zhang Song
Sunkyoung Kang
Sungtae Jung
Wenpei Kang
author_sort Yujie Li
collection DOAJ
description Diabetic Retinopathy (DR) causes quite a few blindness worldwide, which can be refrained by the timely diagnosis on retinal images. Recently, researches on deep learning-based retinal image classification have accelerated outstanding improvements in DR grading task. However, existing DR grading works are mostly limited to a supervised manner. They require accurately annotated data labeled by professional experts, and the annotating work is very laborious and time-consuming. We propose a Semi-supervised Auto-encoder Graph Network (SAGN) for the challenging DR diagnosis to relax this constraint. Precisely, SAGN consists of three major modules: auto-encoder feature learning, neighbor correlation mining, and graph representation. Firstly, our model learns to extract representations from retinal images and reconstruct them as close to original inputs as possible. Then neighbor correlations among labeled and unlabeled samples are established by their similarities, calculated by the radial basis function. Finally, we operate Graph Convolutional Neural Network (GCN) to grade retinal samples from extracted features and their correlations. To evaluate the performance of SAGN, we conduct sufficient comparative experiments on APTOS 2019 dataset, trained from EyePACS. Results demonstrate that our SAGN model can achieve comparable performance with limited labeled retinal images with the help of large amounts of unlabeled data.
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spelling doaj.art-3282de729f1d40ea9d66c38c29d687e02022-12-21T19:11:28ZengIEEEIEEE Access2169-35362021-01-01914075914076710.1109/ACCESS.2021.31194349567704Semi-Supervised Auto-Encoder Graph Network for Diabetic Retinopathy GradingYujie Li0https://orcid.org/0000-0001-8195-4655Zhang Song1https://orcid.org/0000-0002-8240-1742Sunkyoung Kang2https://orcid.org/0000-0002-5888-3710Sungtae Jung3Wenpei Kang4https://orcid.org/0000-0002-0523-4960Weifang Key Laboratory of Blockchain on Agricultural Vegetables, Weifang University of Science and Technology, Weifang, Shandong, ChinaThe Affiliated Hospital of Qingdao University, Qingdao, ChinaDepartment of Computer Software Engineering, Wonkwang University, Iksan, Jeonbuk, Republic of KoreaDepartment of Computer Software Engineering, Wonkwang University, Iksan, Jeonbuk, Republic of KoreaBusiness College of Southwest University, Chongqing, ChinaDiabetic Retinopathy (DR) causes quite a few blindness worldwide, which can be refrained by the timely diagnosis on retinal images. Recently, researches on deep learning-based retinal image classification have accelerated outstanding improvements in DR grading task. However, existing DR grading works are mostly limited to a supervised manner. They require accurately annotated data labeled by professional experts, and the annotating work is very laborious and time-consuming. We propose a Semi-supervised Auto-encoder Graph Network (SAGN) for the challenging DR diagnosis to relax this constraint. Precisely, SAGN consists of three major modules: auto-encoder feature learning, neighbor correlation mining, and graph representation. Firstly, our model learns to extract representations from retinal images and reconstruct them as close to original inputs as possible. Then neighbor correlations among labeled and unlabeled samples are established by their similarities, calculated by the radial basis function. Finally, we operate Graph Convolutional Neural Network (GCN) to grade retinal samples from extracted features and their correlations. To evaluate the performance of SAGN, we conduct sufficient comparative experiments on APTOS 2019 dataset, trained from EyePACS. Results demonstrate that our SAGN model can achieve comparable performance with limited labeled retinal images with the help of large amounts of unlabeled data.https://ieeexplore.ieee.org/document/9567704/Diabetic retinopathy gradingsemi-supervised learningauto-encodergraph convolutional network
spellingShingle Yujie Li
Zhang Song
Sunkyoung Kang
Sungtae Jung
Wenpei Kang
Semi-Supervised Auto-Encoder Graph Network for Diabetic Retinopathy Grading
IEEE Access
Diabetic retinopathy grading
semi-supervised learning
auto-encoder
graph convolutional network
title Semi-Supervised Auto-Encoder Graph Network for Diabetic Retinopathy Grading
title_full Semi-Supervised Auto-Encoder Graph Network for Diabetic Retinopathy Grading
title_fullStr Semi-Supervised Auto-Encoder Graph Network for Diabetic Retinopathy Grading
title_full_unstemmed Semi-Supervised Auto-Encoder Graph Network for Diabetic Retinopathy Grading
title_short Semi-Supervised Auto-Encoder Graph Network for Diabetic Retinopathy Grading
title_sort semi supervised auto encoder graph network for diabetic retinopathy grading
topic Diabetic retinopathy grading
semi-supervised learning
auto-encoder
graph convolutional network
url https://ieeexplore.ieee.org/document/9567704/
work_keys_str_mv AT yujieli semisupervisedautoencodergraphnetworkfordiabeticretinopathygrading
AT zhangsong semisupervisedautoencodergraphnetworkfordiabeticretinopathygrading
AT sunkyoungkang semisupervisedautoencodergraphnetworkfordiabeticretinopathygrading
AT sungtaejung semisupervisedautoencodergraphnetworkfordiabeticretinopathygrading
AT wenpeikang semisupervisedautoencodergraphnetworkfordiabeticretinopathygrading