Molecular mechanisms underlying osteoarthritis development: Notch and NF-κB
Abstract Osteoarthritis (OA) is a multi-factorial and highly prevalent joint disorder worldwide. Since the establishment of murine surgical knee OA models in 2005, many of the key molecules and signalling pathways responsible for OA development have been identified. Here we review the roles of two m...
Main Authors: | Taku Saito, Sakae Tanaka |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-05-01
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Series: | Arthritis Research & Therapy |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13075-017-1296-y |
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