Transcriptional induction of NF-κB-inducing kinase by E2F4/5 facilitates collective invasion of GBM cells

Transcriptional induction of NF-κB-inducing kinase by E2F4/5 facilitates collective invasion of GBM cells

Abstract The prognosis of high-grade gliomas, such as glioblastoma multiforme (GBM), is extremely poor due to the highly invasive nature of these aggressive cancers. Previous work has demonstrated that TNF-weak like factor (TWEAK) induction of the noncanonical NF-κB pathway promotes the invasiveness...

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Bibliographic Details
Main Authors:	Kathryn M. Pflug, Dong W. Lee, Kassandra McFadden, Linda Herrera, Raquel Sitcheran
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-08-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-023-38996-9

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