Digital gene-expression of alfalfa saponin extract on laying hens
Cardiovascular disease is a major cause of death worldwide, so people are advised to limit their intake of dietary cholesterol [1]. Egg consumption has been seriously reduced because of the high levels of cholesterol [2]. The objective of this study was to evaluate the cholesterol metabolism effects...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
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Elsevier
2015-03-01
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Series: | Genomics Data |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2213596014001329 |
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author | Wenna Fan Hongqi Du Lu Zhou Pengfei Shi Chengzhang Wang |
author_facet | Wenna Fan Hongqi Du Lu Zhou Pengfei Shi Chengzhang Wang |
author_sort | Wenna Fan |
collection | DOAJ |
description | Cardiovascular disease is a major cause of death worldwide, so people are advised to limit their intake of dietary cholesterol [1]. Egg consumption has been seriously reduced because of the high levels of cholesterol [2]. The objective of this study was to evaluate the cholesterol metabolism effects of alfalfa saponin extract (ASE) in liver and ovary tissues using digital gene-expression (DGE) profiling analysis. The liver and ovary tissues were isolated from laying hens fed with ASE for RNA sequencing. Here, we provide detailed experimental methods and analysis pipeline in our study to identify digital gene expression of alfalfa saponin extract on laying hens and analysis pipeline published by Singh and colleagues in the PLOS ONE [3]. The data generated in our work provide meaningful information for understanding the molecular mechanisms underlying the cholesterol-lowering effects of ASE. |
first_indexed | 2024-04-13T03:30:44Z |
format | Article |
id | doaj.art-3288c17b409147b1a029f0a94c97ab1a |
institution | Directory Open Access Journal |
issn | 2213-5960 |
language | English |
last_indexed | 2024-04-13T03:30:44Z |
publishDate | 2015-03-01 |
publisher | Elsevier |
record_format | Article |
series | Genomics Data |
spelling | doaj.art-3288c17b409147b1a029f0a94c97ab1a2022-12-22T03:04:29ZengElsevierGenomics Data2213-59602015-03-013C979910.1016/j.gdata.2014.12.003Digital gene-expression of alfalfa saponin extract on laying hensWenna FanHongqi DuLu ZhouPengfei ShiChengzhang WangCardiovascular disease is a major cause of death worldwide, so people are advised to limit their intake of dietary cholesterol [1]. Egg consumption has been seriously reduced because of the high levels of cholesterol [2]. The objective of this study was to evaluate the cholesterol metabolism effects of alfalfa saponin extract (ASE) in liver and ovary tissues using digital gene-expression (DGE) profiling analysis. The liver and ovary tissues were isolated from laying hens fed with ASE for RNA sequencing. Here, we provide detailed experimental methods and analysis pipeline in our study to identify digital gene expression of alfalfa saponin extract on laying hens and analysis pipeline published by Singh and colleagues in the PLOS ONE [3]. The data generated in our work provide meaningful information for understanding the molecular mechanisms underlying the cholesterol-lowering effects of ASE.http://www.sciencedirect.com/science/article/pii/S2213596014001329Digital gene-expressionAlfalfa saponinLaying hens |
spellingShingle | Wenna Fan Hongqi Du Lu Zhou Pengfei Shi Chengzhang Wang Digital gene-expression of alfalfa saponin extract on laying hens Genomics Data Digital gene-expression Alfalfa saponin Laying hens |
title | Digital gene-expression of alfalfa saponin extract on laying hens |
title_full | Digital gene-expression of alfalfa saponin extract on laying hens |
title_fullStr | Digital gene-expression of alfalfa saponin extract on laying hens |
title_full_unstemmed | Digital gene-expression of alfalfa saponin extract on laying hens |
title_short | Digital gene-expression of alfalfa saponin extract on laying hens |
title_sort | digital gene expression of alfalfa saponin extract on laying hens |
topic | Digital gene-expression Alfalfa saponin Laying hens |
url | http://www.sciencedirect.com/science/article/pii/S2213596014001329 |
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