Digital gene-expression of alfalfa saponin extract on laying hens

Cardiovascular disease is a major cause of death worldwide, so people are advised to limit their intake of dietary cholesterol [1]. Egg consumption has been seriously reduced because of the high levels of cholesterol [2]. The objective of this study was to evaluate the cholesterol metabolism effects...

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Main Authors: Wenna Fan, Hongqi Du, Lu Zhou, Pengfei Shi, Chengzhang Wang
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:Genomics Data
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213596014001329
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author Wenna Fan
Hongqi Du
Lu Zhou
Pengfei Shi
Chengzhang Wang
author_facet Wenna Fan
Hongqi Du
Lu Zhou
Pengfei Shi
Chengzhang Wang
author_sort Wenna Fan
collection DOAJ
description Cardiovascular disease is a major cause of death worldwide, so people are advised to limit their intake of dietary cholesterol [1]. Egg consumption has been seriously reduced because of the high levels of cholesterol [2]. The objective of this study was to evaluate the cholesterol metabolism effects of alfalfa saponin extract (ASE) in liver and ovary tissues using digital gene-expression (DGE) profiling analysis. The liver and ovary tissues were isolated from laying hens fed with ASE for RNA sequencing. Here, we provide detailed experimental methods and analysis pipeline in our study to identify digital gene expression of alfalfa saponin extract on laying hens and analysis pipeline published by Singh and colleagues in the PLOS ONE [3]. The data generated in our work provide meaningful information for understanding the molecular mechanisms underlying the cholesterol-lowering effects of ASE.
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spelling doaj.art-3288c17b409147b1a029f0a94c97ab1a2022-12-22T03:04:29ZengElsevierGenomics Data2213-59602015-03-013C979910.1016/j.gdata.2014.12.003Digital gene-expression of alfalfa saponin extract on laying hensWenna FanHongqi DuLu ZhouPengfei ShiChengzhang WangCardiovascular disease is a major cause of death worldwide, so people are advised to limit their intake of dietary cholesterol [1]. Egg consumption has been seriously reduced because of the high levels of cholesterol [2]. The objective of this study was to evaluate the cholesterol metabolism effects of alfalfa saponin extract (ASE) in liver and ovary tissues using digital gene-expression (DGE) profiling analysis. The liver and ovary tissues were isolated from laying hens fed with ASE for RNA sequencing. Here, we provide detailed experimental methods and analysis pipeline in our study to identify digital gene expression of alfalfa saponin extract on laying hens and analysis pipeline published by Singh and colleagues in the PLOS ONE [3]. The data generated in our work provide meaningful information for understanding the molecular mechanisms underlying the cholesterol-lowering effects of ASE.http://www.sciencedirect.com/science/article/pii/S2213596014001329Digital gene-expressionAlfalfa saponinLaying hens
spellingShingle Wenna Fan
Hongqi Du
Lu Zhou
Pengfei Shi
Chengzhang Wang
Digital gene-expression of alfalfa saponin extract on laying hens
Genomics Data
Digital gene-expression
Alfalfa saponin
Laying hens
title Digital gene-expression of alfalfa saponin extract on laying hens
title_full Digital gene-expression of alfalfa saponin extract on laying hens
title_fullStr Digital gene-expression of alfalfa saponin extract on laying hens
title_full_unstemmed Digital gene-expression of alfalfa saponin extract on laying hens
title_short Digital gene-expression of alfalfa saponin extract on laying hens
title_sort digital gene expression of alfalfa saponin extract on laying hens
topic Digital gene-expression
Alfalfa saponin
Laying hens
url http://www.sciencedirect.com/science/article/pii/S2213596014001329
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AT pengfeishi digitalgeneexpressionofalfalfasaponinextractonlayinghens
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