Helicobacter pylori increases the risk of carotid plaque formation: a clinical evidence
AbstractBackground and aim: Since the relation between Helicobacter pylori (H. pylori) and atherosclerosis has been evidenced, we aimed to analyze whether there is a relationship between the patient's H. pylori infection and age, gender, BMI, blood lipids, and carotid plaque formation.Methods:...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2021-01-01
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| Series: | Annals of Medicine |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/07853890.2021.1927169 |
| _version_ | 1797385684200194048 |
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| author | Haiqing Liang Shuzhu Lin Yongjian Ji Yang Xiao Guifang Zheng |
| author_facet | Haiqing Liang Shuzhu Lin Yongjian Ji Yang Xiao Guifang Zheng |
| author_sort | Haiqing Liang |
| collection | DOAJ |
| description | AbstractBackground and aim: Since the relation between Helicobacter pylori (H. pylori) and atherosclerosis has been evidenced, we aimed to analyze whether there is a relationship between the patient's H. pylori infection and age, gender, BMI, blood lipids, and carotid plaque formation.Methods: 810 patients from January 2016 to December 2019 were enrolled in this study, and divided the subjects into H. pylori (+) group and H. pylori (-) group based on the results of UBT. To analyze whether H. pylori infection is related to gender, age, BMI, blood lipids, and neck vascular plaque formation.Results: The single-factor analysis showed that the BMI ≥ 25kg/m2, triglycerides >1.7 mmol/l, the formation of cervical plaques were significantly higher in patients infected with H. pylori in compared to normal cases. Also, multi-variant logistic regression analysis showed that H. pylori infection affects the BMI ≥ 25kg/m2 and triglycerides >1.7 mmol/l to induce vascular plaque. Also, we showed that patients with H. pylori infection are 1.424 times higher than the non-infected group to have triglycerides more elevated than 1.7mmol/l.Conclusion: In this study, we conclude that H. pylori infection is an independent risk factor for higher BMI (>25), triglyceride (>1.7 mmol/l), and neck vascular plaque formation. The multi-variant analysis showed that patients with H. pylori infection are prone to have higher BMI, triglycerides, and neck vascular plaque formation over 1.4-times higher in non-infected individuals.KEY MESSAGESH. pylori infection is an independent risk factor for higher BMI, triglyceride, and neck vascular plaque formation.H. pylori can accelerate vascular plaque formation through increasing BMI and triglyceride. |
| first_indexed | 2024-03-08T21:57:51Z |
| format | Article |
| id | doaj.art-328aab1de7504cfab77b0d2fb712be2f |
| institution | Directory Open Access Journal |
| issn | 0785-3890 1365-2060 |
| language | English |
| last_indexed | 2024-03-08T21:57:51Z |
| publishDate | 2021-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Annals of Medicine |
| spelling | doaj.art-328aab1de7504cfab77b0d2fb712be2f2023-12-19T16:46:27ZengTaylor & Francis GroupAnnals of Medicine0785-38901365-20602021-01-015311448145410.1080/07853890.2021.1927169Helicobacter pylori increases the risk of carotid plaque formation: a clinical evidenceHaiqing Liang0Shuzhu Lin1Yongjian Ji2Yang Xiao3Guifang Zheng4Department of Internal Medicine, Dezhou People's Hospital, Dezhou, ChinaDepartment of Clinical Laboratory, Dezhou People's Hospital, Dezhou, ChinaDepartment of Internal Medicine, Dezhou People's Hospital, Dezhou, ChinaDepartment of Internal Medicine, Dezhou People's Hospital, Dezhou, ChinaDepartment of Internal Medicine, Dezhou People's Hospital, Dezhou, ChinaAbstractBackground and aim: Since the relation between Helicobacter pylori (H. pylori) and atherosclerosis has been evidenced, we aimed to analyze whether there is a relationship between the patient's H. pylori infection and age, gender, BMI, blood lipids, and carotid plaque formation.Methods: 810 patients from January 2016 to December 2019 were enrolled in this study, and divided the subjects into H. pylori (+) group and H. pylori (-) group based on the results of UBT. To analyze whether H. pylori infection is related to gender, age, BMI, blood lipids, and neck vascular plaque formation.Results: The single-factor analysis showed that the BMI ≥ 25kg/m2, triglycerides >1.7 mmol/l, the formation of cervical plaques were significantly higher in patients infected with H. pylori in compared to normal cases. Also, multi-variant logistic regression analysis showed that H. pylori infection affects the BMI ≥ 25kg/m2 and triglycerides >1.7 mmol/l to induce vascular plaque. Also, we showed that patients with H. pylori infection are 1.424 times higher than the non-infected group to have triglycerides more elevated than 1.7mmol/l.Conclusion: In this study, we conclude that H. pylori infection is an independent risk factor for higher BMI (>25), triglyceride (>1.7 mmol/l), and neck vascular plaque formation. The multi-variant analysis showed that patients with H. pylori infection are prone to have higher BMI, triglycerides, and neck vascular plaque formation over 1.4-times higher in non-infected individuals.KEY MESSAGESH. pylori infection is an independent risk factor for higher BMI, triglyceride, and neck vascular plaque formation.H. pylori can accelerate vascular plaque formation through increasing BMI and triglyceride.https://www.tandfonline.com/doi/10.1080/07853890.2021.1927169Helicobacter pylorilesion formationcervical vesseldyslipidemiaBMI |
| spellingShingle | Haiqing Liang Shuzhu Lin Yongjian Ji Yang Xiao Guifang Zheng Helicobacter pylori increases the risk of carotid plaque formation: a clinical evidence Annals of Medicine Helicobacter pylori lesion formation cervical vessel dyslipidemia BMI |
| title | Helicobacter pylori increases the risk of carotid plaque formation: a clinical evidence |
| title_full | Helicobacter pylori increases the risk of carotid plaque formation: a clinical evidence |
| title_fullStr | Helicobacter pylori increases the risk of carotid plaque formation: a clinical evidence |
| title_full_unstemmed | Helicobacter pylori increases the risk of carotid plaque formation: a clinical evidence |
| title_short | Helicobacter pylori increases the risk of carotid plaque formation: a clinical evidence |
| title_sort | helicobacter pylori increases the risk of carotid plaque formation a clinical evidence |
| topic | Helicobacter pylori lesion formation cervical vessel dyslipidemia BMI |
| url | https://www.tandfonline.com/doi/10.1080/07853890.2021.1927169 |
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