Therapy-Induced Stromal Senescence Promoting Aggressiveness of Prostate and Ovarian Cancer

Therapy-Induced Stromal Senescence Promoting Aggressiveness of Prostate and Ovarian Cancer

Cancer progression is supported by the cross-talk between tumor cells and the surrounding stroma. In this context, senescent cells in the tumor microenvironment contribute to the development of a pro-inflammatory milieu and the acquisition of aggressive traits by cancer cells. Anticancer treatments...

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Bibliographic Details
Main Authors: Elisa Pardella, Erica Pranzini, Ilaria Nesi, Matteo Parri, Pietro Spatafora, Eugenio Torre, Angela Muccilli, Francesca Castiglione, Massimiliano Fambrini, Flavia Sorbi, Paolo Cirri, Anna Caselli, Martin Puhr, Helmut Klocker, Sergio Serni, Giovanni Raugei, Francesca Magherini, Maria Letizia Taddei
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
prostate cancer
ovarian cancer
therapy induced senescence
tumor microenvironment
docetaxel
cisplatin
Online Access:https://www.mdpi.com/2073-4409/11/24/4026

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