Development of 3D-Bioprinted Colitis-Mimicking Model to Assess Epithelial Barrier Function Using Albumin Nano-Encapsulated Anti-Inflammatory Drugs

Development of 3D-Bioprinted Colitis-Mimicking Model to Assess Epithelial Barrier Function Using Albumin Nano-Encapsulated Anti-Inflammatory Drugs

Physiological barrier function is very difficult to replicate in vitro. This situation leads to poor prediction of candidate drugs in the drug development process due to the lack of preclinical modelling for intestinal function. By using 3D bioprinting, we generated a colitis-like condition model th...

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Bibliographic Details
Main Authors: Abdulmajeed G. Almutary, Abdullah M. Alnuqaydan, Saleh A. Almatroodi, Hamid A. Bakshi, Dinesh Kumar Chellappan, Murtaza M. Tambuwala
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Biomimetics
Subjects:
3D bioprinting
colitis 3D model
drug prediction
barrier function
albumin nanoparticles
Roxadustat
Online Access:https://www.mdpi.com/2313-7673/8/1/41

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