REPRODUCTIVE OUTCOME, DURATION OF PREGNANCY AND MODE OF DELIVERY AFTER HYSTEROSCOPIC METROPLASTY IN PATIENTS WITH INFERTILITY

Introduction: Reproductive outcome can be negatively affected in patients with congenital uterine anomalies (CUA), increasing the number of unsuccessful pregnancies and obstetric complications. Standard, safe and minimally invasive method for the treatment of correctible types of congenital uterine...

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Main Authors: Tofoski Gligor, Dimitrov Goran, Hadzi-Lega Marija, Dzikova Elena
Format: Article
Language:English
Published: Association of medical doctors Sanamed Novi Pazar 2016-07-01
Series:Sanamed
Subjects:
Online Access:http://www.sanamed.rs/OJS/index.php/Sanamed/article/view/134/55
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author Tofoski Gligor
Dimitrov Goran
Hadzi-Lega Marija
Dzikova Elena
author_facet Tofoski Gligor
Dimitrov Goran
Hadzi-Lega Marija
Dzikova Elena
author_sort Tofoski Gligor
collection DOAJ
description Introduction: Reproductive outcome can be negatively affected in patients with congenital uterine anomalies (CUA), increasing the number of unsuccessful pregnancies and obstetric complications. Standard, safe and minimally invasive method for the treatment of correctible types of congenital uterine anomalies is hysteroscopic metroplasty (HM). The aim of the study was to analyze the reproductive outcome, duration of pregnancy and mode of delivery in group of patients with infertility after hysteroscopic metroplasty. Material and methods: We analyzed 48 patients with previous history of fetal loss (abortion) to whom hysteroscopy was done in the period of 01.11.2009 to 01.05.2013 year at the University Clinic of Obstetrics and Gynecology in Skopje. In patients who were diagnosed having CUA hysteroscopic metroplasty was done. Patients and their reproductive outcome were followed for a period of at least 2 years after the intervention. Reproductive outcome was followed considering pregnancy rate, fetal loss (abortion) up to 22 gestational week, rates of preterm and term deliveries, live births and mode of delivery. Statistical analysis was performed using computer software and value for the confidence interval (± 95% CI) was considered to be statistically significant with level of p<0.05. Results: After hysteroscopic metroplasty, there was a significant decrease of the abortion rate to 13.9%, and significant increase in pregnancy rates of 86.1%. Overall pregnancy rate was 75%, and term delivery was noted in 93,6 % of the patients, with spontaneus deliveries in 58,6 %. There were no complications during the hysteroscopic metroplasty, nor during the deliveries. Conclusion: Hysteroscopic metroplasty has a significant effect on the reproductive outcome, resulting in a large number of live births and no significant complication during consecutive pregnancy and delivery.
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spelling doaj.art-32946511cf8a4810b5c4eeccaee8c0572024-03-02T07:52:27ZengAssociation of medical doctors Sanamed Novi PazarSanamed1452-662X2217-81712016-07-0111211712210.5937/sanamed1602117TREPRODUCTIVE OUTCOME, DURATION OF PREGNANCY AND MODE OF DELIVERY AFTER HYSTEROSCOPIC METROPLASTY IN PATIENTS WITH INFERTILITYTofoski Gligor0Dimitrov Goran1Hadzi-Lega Marija2Dzikova Elena3PHI University Clinic of Gynecology and Obstetrics, Medical Faculty, University ”St. Cyril and Methodius” - Skopje, Republic of MacedoniaPHI University Clinic of Gynecology and Obstetrics, Medical Faculty, University ”St. Cyril and Methodius” - Skopje, Republic of MacedoniaPHI University Clinic of Gynecology and Obstetrics, Medical Faculty, University ”St. Cyril and Methodius” - Skopje, Republic of MacedoniaPHI University Clinic of Gynecology and Obstetrics, Medical Faculty, University ”St. Cyril and Methodius” - Skopje, Republic of MacedoniaIntroduction: Reproductive outcome can be negatively affected in patients with congenital uterine anomalies (CUA), increasing the number of unsuccessful pregnancies and obstetric complications. Standard, safe and minimally invasive method for the treatment of correctible types of congenital uterine anomalies is hysteroscopic metroplasty (HM). The aim of the study was to analyze the reproductive outcome, duration of pregnancy and mode of delivery in group of patients with infertility after hysteroscopic metroplasty. Material and methods: We analyzed 48 patients with previous history of fetal loss (abortion) to whom hysteroscopy was done in the period of 01.11.2009 to 01.05.2013 year at the University Clinic of Obstetrics and Gynecology in Skopje. In patients who were diagnosed having CUA hysteroscopic metroplasty was done. Patients and their reproductive outcome were followed for a period of at least 2 years after the intervention. Reproductive outcome was followed considering pregnancy rate, fetal loss (abortion) up to 22 gestational week, rates of preterm and term deliveries, live births and mode of delivery. Statistical analysis was performed using computer software and value for the confidence interval (± 95% CI) was considered to be statistically significant with level of p<0.05. Results: After hysteroscopic metroplasty, there was a significant decrease of the abortion rate to 13.9%, and significant increase in pregnancy rates of 86.1%. Overall pregnancy rate was 75%, and term delivery was noted in 93,6 % of the patients, with spontaneus deliveries in 58,6 %. There were no complications during the hysteroscopic metroplasty, nor during the deliveries. Conclusion: Hysteroscopic metroplasty has a significant effect on the reproductive outcome, resulting in a large number of live births and no significant complication during consecutive pregnancy and delivery.http://www.sanamed.rs/OJS/index.php/Sanamed/article/view/134/55hysteroscopymetroplastyreproductioninfertilitypregnancydelivery
spellingShingle Tofoski Gligor
Dimitrov Goran
Hadzi-Lega Marija
Dzikova Elena
REPRODUCTIVE OUTCOME, DURATION OF PREGNANCY AND MODE OF DELIVERY AFTER HYSTEROSCOPIC METROPLASTY IN PATIENTS WITH INFERTILITY
Sanamed
hysteroscopy
metroplasty
reproduction
infertility
pregnancy
delivery
title REPRODUCTIVE OUTCOME, DURATION OF PREGNANCY AND MODE OF DELIVERY AFTER HYSTEROSCOPIC METROPLASTY IN PATIENTS WITH INFERTILITY
title_full REPRODUCTIVE OUTCOME, DURATION OF PREGNANCY AND MODE OF DELIVERY AFTER HYSTEROSCOPIC METROPLASTY IN PATIENTS WITH INFERTILITY
title_fullStr REPRODUCTIVE OUTCOME, DURATION OF PREGNANCY AND MODE OF DELIVERY AFTER HYSTEROSCOPIC METROPLASTY IN PATIENTS WITH INFERTILITY
title_full_unstemmed REPRODUCTIVE OUTCOME, DURATION OF PREGNANCY AND MODE OF DELIVERY AFTER HYSTEROSCOPIC METROPLASTY IN PATIENTS WITH INFERTILITY
title_short REPRODUCTIVE OUTCOME, DURATION OF PREGNANCY AND MODE OF DELIVERY AFTER HYSTEROSCOPIC METROPLASTY IN PATIENTS WITH INFERTILITY
title_sort reproductive outcome duration of pregnancy and mode of delivery after hysteroscopic metroplasty in patients with infertility
topic hysteroscopy
metroplasty
reproduction
infertility
pregnancy
delivery
url http://www.sanamed.rs/OJS/index.php/Sanamed/article/view/134/55
work_keys_str_mv AT tofoskigligor reproductiveoutcomedurationofpregnancyandmodeofdeliveryafterhysteroscopicmetroplastyinpatientswithinfertility
AT dimitrovgoran reproductiveoutcomedurationofpregnancyandmodeofdeliveryafterhysteroscopicmetroplastyinpatientswithinfertility
AT hadzilegamarija reproductiveoutcomedurationofpregnancyandmodeofdeliveryafterhysteroscopicmetroplastyinpatientswithinfertility
AT dzikovaelena reproductiveoutcomedurationofpregnancyandmodeofdeliveryafterhysteroscopicmetroplastyinpatientswithinfertility