Randomizing of Oligopeptide Conformations by Nearest Neighbor Interactions between Amino Acid Residues

Randomizing of Oligopeptide Conformations by Nearest Neighbor Interactions between Amino Acid Residues

Flory’s random coil model assumes that conformational fluctuations of amino acid residues in unfolded poly(oligo)peptides and proteins are uncorrelated (isolated pair hypothesis, IPH). This implies that conformational energies, entropies and solvation free energies are all additive. Nearly 25 years...

Full description

Bibliographic Details
Main Authors: Reinhard Schweitzer-Stenner, Bridget Milorey, Harald Schwalbe
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biomolecules
Subjects:
Ramachandran distributions
isolated pair hypothesis
nearest neighbor interactions
model peptides
intrinsically disordered proteins
Online Access:https://www.mdpi.com/2218-273X/12/5/684

Internet

https://www.mdpi.com/2218-273X/12/5/684

Similar Items