Evaluation of Bactericidal Activity of Electrochemical GO Modified with TiO2 Nanoparticles
Recently, antibacterial materials have sparked a renewed interest in the fields of biomedical engineering and life sciences. The main purpose of this study was to evaluate the physicochemical properties of TiO2 nanoparticles with anatase phase and an average size of 24.1 ± 4.6 nm, graphene oxide (GO...
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| Format: | Article |
| Language: | English |
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Instituto Tecnológico Metropolitano
2023-12-01
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| Series: | TecnoLógicas |
| Subjects: | |
| Online Access: | https://revistas.itm.edu.co/index.php/tecnologicas/article/view/2765 |
| _version_ | 1827354967285956608 |
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| author | Geraldine Durango Giraldo* Juan Camilo Zapata-Hernández Claudia Betancur Henao Juan Felipe Santa Marín Robison Buitrago Sierra |
| author_facet | Geraldine Durango Giraldo* Juan Camilo Zapata-Hernández Claudia Betancur Henao Juan Felipe Santa Marín Robison Buitrago Sierra |
| author_sort | Geraldine Durango Giraldo* |
| collection | DOAJ |
| description | Recently, antibacterial materials have sparked a renewed interest in the fields of biomedical engineering and life sciences. The main purpose of this study was to evaluate the physicochemical properties of TiO2 nanoparticles with anatase phase and an average size of 24.1 ± 4.6 nm, graphene oxide (GO) obtained from the electrochemical method, and TiO2/GO hybrid nanomaterial. Thermogravimetric analysis (TGA) revealed the presence of oxygen functionalities in the GO structure and 23.2 % of TiO2 in the hybrid nanomaterial, as well as a strong interaction between the materials that can be observed in the micrograph of scanning electron microscopy (SEM). Antibacterial tests were performed using the macrodilution method. The results showed that, while GO did not decrease bacterial growth, TiO2 presented high bactericidal activity. In turn, the hybrid TiO2/GO nanomaterial did not show such activity. This result can be explained by the decrease in contact between TiO2 and bacterial cells due to the blocking of the active sites on the TiO2 surface by graphene oxide sheets. These results contribute to the ongoing discussion about the bactericidal properties of graphene oxide. |
| first_indexed | 2024-03-08T04:02:24Z |
| format | Article |
| id | doaj.art-3296a97f55a546b4b8b4e5fae2ba3397 |
| institution | Directory Open Access Journal |
| issn | 0123-7799 2256-5337 |
| language | English |
| last_indexed | 2024-03-08T04:02:24Z |
| publishDate | 2023-12-01 |
| publisher | Instituto Tecnológico Metropolitano |
| record_format | Article |
| series | TecnoLógicas |
| spelling | doaj.art-3296a97f55a546b4b8b4e5fae2ba33972024-02-09T14:31:42ZengInstituto Tecnológico MetropolitanoTecnoLógicas0123-77992256-53372023-12-012658e2765e276510.22430/22565337.27652310Evaluation of Bactericidal Activity of Electrochemical GO Modified with TiO2 NanoparticlesGeraldine Durango Giraldo*0https://orcid.org/0000-0002-7799-4790Juan Camilo Zapata-Hernández1https://orcid.org/0000-0002-8664-5867Claudia Betancur Henao2https://orcid.org/0000-0003-1345-9091Juan Felipe Santa Marín3https://orcid.org/0000-0001-5781-672XRobison Buitrago Sierra4https://orcid.org/0000-0002-5995-4031Instituto Tecnológico Metropolitano, ColombiaInstituto Tecnológico Metropolitano, ColombiaInstituto Tecnológico Metropolitano, ColombiaInstituto Tecnológico Metropolitano, ColombiaInstituto Tecnológico Metropolitano, ColombiaRecently, antibacterial materials have sparked a renewed interest in the fields of biomedical engineering and life sciences. The main purpose of this study was to evaluate the physicochemical properties of TiO2 nanoparticles with anatase phase and an average size of 24.1 ± 4.6 nm, graphene oxide (GO) obtained from the electrochemical method, and TiO2/GO hybrid nanomaterial. Thermogravimetric analysis (TGA) revealed the presence of oxygen functionalities in the GO structure and 23.2 % of TiO2 in the hybrid nanomaterial, as well as a strong interaction between the materials that can be observed in the micrograph of scanning electron microscopy (SEM). Antibacterial tests were performed using the macrodilution method. The results showed that, while GO did not decrease bacterial growth, TiO2 presented high bactericidal activity. In turn, the hybrid TiO2/GO nanomaterial did not show such activity. This result can be explained by the decrease in contact between TiO2 and bacterial cells due to the blocking of the active sites on the TiO2 surface by graphene oxide sheets. These results contribute to the ongoing discussion about the bactericidal properties of graphene oxide.https://revistas.itm.edu.co/index.php/tecnologicas/article/view/2765bacterial activityhybrid nanomaterialgraphene oxidetitanium dioxide |
| spellingShingle | Geraldine Durango Giraldo* Juan Camilo Zapata-Hernández Claudia Betancur Henao Juan Felipe Santa Marín Robison Buitrago Sierra Evaluation of Bactericidal Activity of Electrochemical GO Modified with TiO2 Nanoparticles TecnoLógicas bacterial activity hybrid nanomaterial graphene oxide titanium dioxide |
| title | Evaluation of Bactericidal Activity of Electrochemical GO Modified with TiO2 Nanoparticles |
| title_full | Evaluation of Bactericidal Activity of Electrochemical GO Modified with TiO2 Nanoparticles |
| title_fullStr | Evaluation of Bactericidal Activity of Electrochemical GO Modified with TiO2 Nanoparticles |
| title_full_unstemmed | Evaluation of Bactericidal Activity of Electrochemical GO Modified with TiO2 Nanoparticles |
| title_short | Evaluation of Bactericidal Activity of Electrochemical GO Modified with TiO2 Nanoparticles |
| title_sort | evaluation of bactericidal activity of electrochemical go modified with tio2 nanoparticles |
| topic | bacterial activity hybrid nanomaterial graphene oxide titanium dioxide |
| url | https://revistas.itm.edu.co/index.php/tecnologicas/article/view/2765 |
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