Composition and Antioxidative and Antibacterial Activities of the Essential Oil from <i>Farfugium japonicum</i>
The composition of volatile oils of the leaf and stem of <i>Farfugium japonicum</i> (L.) Kitamura were prepared by supercritical fluid extraction (SFE)-CO<sub>2</sub>. A total 47 and 40 compounds were identified by GC/MS analysis, respectively, and only 13 compounds coexisted...
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MDPI AG
2023-03-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/28/6/2774 |
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| author | Qiang Wei Yi-Han Zhang |
| author_facet | Qiang Wei Yi-Han Zhang |
| author_sort | Qiang Wei |
| collection | DOAJ |
| description | The composition of volatile oils of the leaf and stem of <i>Farfugium japonicum</i> (L.) Kitamura were prepared by supercritical fluid extraction (SFE)-CO<sub>2</sub>. A total 47 and 40 compounds were identified by GC/MS analysis, respectively, and only 13 compounds coexisted. The main constituent types in the leaf oil included alcohols (34.1%), hydrocarbons (24.1%), terpenoids (16.2%), benzenes (7.5%), and fatty acids (4.9%). In the stem oil, the constituent types chiefly included benzenes (18.8%), ketones (13.9%), terpenoids (17.0%), fatty acids (8.8%), phenolics (8.7%), steroids (8.6%), hydrocarbons (8.0%), and esters (5.7%). The predominant volatile compounds in the stem were 2-(1-cyclopent-1-enyl-1-methylethyl) cyclopentanone (11.7%), 1,2,3,4,5,6,7,8-octahydro- 9,10-dimethyl-anthracene (8.4%), 5-heptylresorcinol (6.5%), and <i>α</i>-sitosterol (5.2%). Those in the leaf mainly included (<i>E</i>)-3-hexen-1-ol (13.7%) and (<i>Z</i>)-3-hexen-1-ol (14.0%). This demonstrated a significant difference in the composition of both oils. Further study showed that stem oils demonstrated the highest DPPH (1,1-diphenyl-2-pinylhydrazyl) and ·OH free radical scavenging capacities at IC<sub>50</sub> values of 9.22 and 0.90 mg/mL, respectively. In addition, they demonstrated the strongest antibacterial capacity against the Gram-positive bacteria methicillin-sensitive <i>Staphylococcus aureus</i> (MSSA) and methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) at a minimum inhibitory concentration (MIC) of 0.16 mg/mL. This could be due to the SFE-CO<sub>2</sub> extraction and the high accumulation of benzenes, terpenoids, and phenolics in the stem. In particular, the monoterpenes presented in terpenoids could play a special role in these findings. |
| first_indexed | 2024-03-11T06:07:08Z |
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| id | doaj.art-3297548775d94eadb48bc80e626f4284 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-11T06:07:08Z |
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| spelling | doaj.art-3297548775d94eadb48bc80e626f42842023-11-17T12:54:59ZengMDPI AGMolecules1420-30492023-03-01286277410.3390/molecules28062774Composition and Antioxidative and Antibacterial Activities of the Essential Oil from <i>Farfugium japonicum</i>Qiang Wei0Yi-Han Zhang1School of Medicine, Anhui Xinhua University, Hefei 230088, ChinaSchool of Medicine, Anhui Xinhua University, Hefei 230088, ChinaThe composition of volatile oils of the leaf and stem of <i>Farfugium japonicum</i> (L.) Kitamura were prepared by supercritical fluid extraction (SFE)-CO<sub>2</sub>. A total 47 and 40 compounds were identified by GC/MS analysis, respectively, and only 13 compounds coexisted. The main constituent types in the leaf oil included alcohols (34.1%), hydrocarbons (24.1%), terpenoids (16.2%), benzenes (7.5%), and fatty acids (4.9%). In the stem oil, the constituent types chiefly included benzenes (18.8%), ketones (13.9%), terpenoids (17.0%), fatty acids (8.8%), phenolics (8.7%), steroids (8.6%), hydrocarbons (8.0%), and esters (5.7%). The predominant volatile compounds in the stem were 2-(1-cyclopent-1-enyl-1-methylethyl) cyclopentanone (11.7%), 1,2,3,4,5,6,7,8-octahydro- 9,10-dimethyl-anthracene (8.4%), 5-heptylresorcinol (6.5%), and <i>α</i>-sitosterol (5.2%). Those in the leaf mainly included (<i>E</i>)-3-hexen-1-ol (13.7%) and (<i>Z</i>)-3-hexen-1-ol (14.0%). This demonstrated a significant difference in the composition of both oils. Further study showed that stem oils demonstrated the highest DPPH (1,1-diphenyl-2-pinylhydrazyl) and ·OH free radical scavenging capacities at IC<sub>50</sub> values of 9.22 and 0.90 mg/mL, respectively. In addition, they demonstrated the strongest antibacterial capacity against the Gram-positive bacteria methicillin-sensitive <i>Staphylococcus aureus</i> (MSSA) and methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) at a minimum inhibitory concentration (MIC) of 0.16 mg/mL. This could be due to the SFE-CO<sub>2</sub> extraction and the high accumulation of benzenes, terpenoids, and phenolics in the stem. In particular, the monoterpenes presented in terpenoids could play a special role in these findings.https://www.mdpi.com/1420-3049/28/6/2774<i>Farfugium japonicum</i>chemical componentsvolatile oilantioxidative activityantibacterial activity |
| spellingShingle | Qiang Wei Yi-Han Zhang Composition and Antioxidative and Antibacterial Activities of the Essential Oil from <i>Farfugium japonicum</i> Molecules <i>Farfugium japonicum</i> chemical components volatile oil antioxidative activity antibacterial activity |
| title | Composition and Antioxidative and Antibacterial Activities of the Essential Oil from <i>Farfugium japonicum</i> |
| title_full | Composition and Antioxidative and Antibacterial Activities of the Essential Oil from <i>Farfugium japonicum</i> |
| title_fullStr | Composition and Antioxidative and Antibacterial Activities of the Essential Oil from <i>Farfugium japonicum</i> |
| title_full_unstemmed | Composition and Antioxidative and Antibacterial Activities of the Essential Oil from <i>Farfugium japonicum</i> |
| title_short | Composition and Antioxidative and Antibacterial Activities of the Essential Oil from <i>Farfugium japonicum</i> |
| title_sort | composition and antioxidative and antibacterial activities of the essential oil from i farfugium japonicum i |
| topic | <i>Farfugium japonicum</i> chemical components volatile oil antioxidative activity antibacterial activity |
| url | https://www.mdpi.com/1420-3049/28/6/2774 |
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