Hyperhomocysteinemia, intravascular hemostasis disturbances, and clinical course of myocardial infarction
The article is devoted to associations between hyperhomocysteinemia and intravascular hemostasis disturbances in myocardial infarction (MI) patients. The role of these disturbances in post-MI angina and recurrent MI development is analyzed. Fifty-seven MI patients who underwent systemic thrombolysis...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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«FIRMA «SILICEA» LLC
2007-04-01
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| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/2074 |
| Summary: | The article is devoted to associations between hyperhomocysteinemia and intravascular hemostasis disturbances in myocardial infarction (MI) patients. The role of these disturbances in post-MI angina and recurrent MI development is analyzed. Fifty-seven MI patients who underwent systemic thrombolysis were examined. Hyperhomocysteinemia was registered in 16 participants (28%); mean homocysteine level was 21,55±10,26 mkmol/l. Homocysteine concentration correlated significantly with total cholesterol level and platelet aggregation. Inpatients with hyperhomocysteinemia, natural anticoagulants activity was reduced. The data obtained are consistent with the hypothesis that hyperhomocysteinemia is a marker of poor outcome in MI patients. |
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| ISSN: | 1560-4071 2618-7620 |