Direct heme transfer reactions in the Group A Streptococcus heme acquisition pathway.

The heme acquisition machinery in Group A Streptococcus (GAS) consists of the surface proteins Shr and Shp and ATP-binding cassette transporter HtsABC. Shp cannot directly acquire heme from methemoglobin (metHb) but directly transfers its heme to HtsA. It has not been previously determined whether S...

Full description

Bibliographic Details
Main Authors: Chunmei Lu, Gang Xie, Mengyao Liu, Hui Zhu, Benfang Lei
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3359286?pdf=render