Impact of Isoorientin on Metabolic Activity and Lipid Accumulation in Differentiated Adipocytes
The current study explored the effect of isoorientin on the metabolic activity and lipid accumulation in fully differentiated 3T3-L1 adipocytes. To achieve this, the 3T3-L1 pre-adipocytes were differentiated for eight days and treated with various concentrations of isoorientin (0.1–100 μM) for four...
Main Authors: | Khanyisani Ziqubu, Christo J. F. Muller, Phiwayinkosi V. Dludla, Sinenhlanhla X. H. Mthembu, Nnini Obonye, Johan Louw, Abidemi P. Kappo, Sonia Silvestri, Patrick Orlando, Luca Tiano, Sithandiwe E. Mazibuko-Mbeje |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-04-01
|
Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/25/8/1773 |
Similar Items
-
Isoorientin ameliorates lipid accumulation by regulating fat browning in palmitate-exposed 3T3-L1 adipocytes
by: Sithandiwe E. Mazibuko-Mbeje, et al.
Published: (2020-06-01) -
Rooibos Flavonoids, Aspalathin, Isoorientin, and Orientin Ameliorate Antimycin A-Induced Mitochondrial Dysfunction by Improving Mitochondrial Bioenergetics in Cultured Skeletal Muscle Cells
by: Sinenhlanhla X. H. Mthembu, et al.
Published: (2021-10-01) -
Isoorientin Attenuated the Pyroptotic Hepatocyte Damage Induced by Benzo[a]pyrene via ROS/NF-κB/NLRP3/Caspase-1 Signaling Pathway
by: Hao Li, et al.
Published: (2021-08-01) -
Isoorientin Attenuates Cisplatin-Induced Nephrotoxicity Through the Inhibition of Oxidative Stress and Apoptosis via Activating the SIRT1/SIRT6/Nrf-2 Pathway
by: Xiaoye Fan, et al.
Published: (2020-03-01) -
Orientin Improves Substrate Utilization and the Expression of Major Genes Involved in Insulin Signaling and Energy Regulation in Cultured Insulin-Resistant Liver Cells
by: Sithandiwe E. Mazibuko-Mbeje, et al.
Published: (2021-10-01)