Nuclear lamina erosion-induced resurrection of endogenous retroviruses underlies neuronal aging
Summary: The primate frontal lobe (FL) is sensitive to aging-related neurocognitive decline. However, the aging-associated molecular mechanisms remain unclear. Here, using physiologically aged non-human primates (NHPs), we depicted a comprehensive landscape of FL aging with multidimensional profilin...
Main Authors: | Hui Zhang, Jiaming Li, Yang Yu, Jie Ren, Qiang Liu, Zhaoshi Bao, Shuhui Sun, Xiaoqian Liu, Shuai Ma, Zunpeng Liu, Kaowen Yan, Zeming Wu, Yanling Fan, Xiaoyan Sun, Yixin Zhang, Qianzhao Ji, Fang Cheng, Peng-Hu Wei, Xibo Ma, Shiqiang Zhang, Zhengwei Xie, Yuyu Niu, Yan-Jiang Wang, Jing-Dong J. Han, Tao Jiang, Guoguang Zhao, Weizhi Ji, Juan Carlos Izpisua Belmonte, Si Wang, Jing Qu, Weiqi Zhang, Guang-Hui Liu |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-06-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124723006046 |
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