Use of p38 MAPK Inhibitors for the Treatment of Werner Syndrome

Use of p38 MAPK Inhibitors for the Treatment of Werner Syndrome

Werner syndrome provides a convincing model for aspects of the normal ageing phenotype and may provide a suitable model for therapeutic interventions designed to combat the ageing process. Cultured primary fibroblast cells from Werner syndrome patients provide a powerful model system to study the li...

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Bibliographic Details
Main Authors: Mark C. Bagley, Terence Davis, Paola G. S. Murziani, Caroline S. Widdowson, David Kipling
Format: Article
Language:English
Published: MDPI AG 2010-06-01
Series:Pharmaceuticals
Subjects:
accelerated ageing
inflammation
microwave-assisted synthesis
p38 MAPK
progeroid syndrome
Werner syndrome
Online Access:http://www.mdpi.com/1424-8247/3/6/1842/

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