The impact of clinical presentation, presence of SIRS and organ dysfunction on mortality in bitches with pyometra
ABSTRACT: This retrospective study evaluated the impact of the clinical presentation of pyometra on the morbidity and mortality of the affected bitches. The medical records of 47 bitches surgically treated for pyometra between May and December 2017 were evaluated. The admission data were analyzed to...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Universidade Federal de Santa Maria
2023-06-01
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| Series: | Ciência Rural |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782024000100603&tlng=en |
| _version_ | 1797791369180217344 |
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| author | Anna Julia Rodrigues Peixoto Virgínia Conceição Tavares Lima Maria Eduarda dos Santos Lopes Fernandes Lucinéia Costa Oliveira Beatriz Teixeira Blanc Felipe Farias Pereira da Câmara Barros Fabiana Batalha Knackfuss Cristiane Divan Baldani Cássia Maria Molinaro Coelho |
| author_facet | Anna Julia Rodrigues Peixoto Virgínia Conceição Tavares Lima Maria Eduarda dos Santos Lopes Fernandes Lucinéia Costa Oliveira Beatriz Teixeira Blanc Felipe Farias Pereira da Câmara Barros Fabiana Batalha Knackfuss Cristiane Divan Baldani Cássia Maria Molinaro Coelho |
| author_sort | Anna Julia Rodrigues Peixoto |
| collection | DOAJ |
| description | ABSTRACT: This retrospective study evaluated the impact of the clinical presentation of pyometra on the morbidity and mortality of the affected bitches. The medical records of 47 bitches surgically treated for pyometra between May and December 2017 were evaluated. The admission data were analyzed to classify the animals according to the clinical presentation of pyometra, presence of systemic inflammatory response syndrome (SIRS) and organic dysfunctions (cardiovascular, neurological, renal, and hemostatic). The outcomes were recorded for up to 14 days. The overall mortality rate was 13%. Open and closed pyometra were identified in 62% (n= 29) and 38% (n= 18) of the cases, respectively. The SIRS was present in 44 (94%) bitches, and 27 (57%) had at least one organ dysfunction. The most prevalent dysfunction was hemostatic, followed by neurological, cardiovascular, and renal dysfunction. The clinical presentation of pyometra and the presence of SIRS did not correlate with each other, or with the presence of organ dysfunction and mortality. However, cumulative organ dysfunction (r=0.532, P=<0.001) and the presence of neurological (r= -0.371; P=0.012) and renal dysfunction (r=0.303; P=0.041) were correlated with mortality. Thus, the identification of organ dysfunction through physical examination and routine laboratory analysis proved to be more effective in identifying and predicting the critically ill patients than the SIRS criteria or clinical presentation of the disease. |
| first_indexed | 2024-03-13T02:17:48Z |
| format | Article |
| id | doaj.art-32ad0ae42bd44f34b8361abb30a673e9 |
| institution | Directory Open Access Journal |
| issn | 1678-4596 |
| language | English |
| last_indexed | 2024-03-13T02:17:48Z |
| publishDate | 2023-06-01 |
| publisher | Universidade Federal de Santa Maria |
| record_format | Article |
| series | Ciência Rural |
| spelling | doaj.art-32ad0ae42bd44f34b8361abb30a673e92023-06-30T10:59:59ZengUniversidade Federal de Santa MariaCiência Rural1678-45962023-06-0154110.1590/0103-8478cr20220219The impact of clinical presentation, presence of SIRS and organ dysfunction on mortality in bitches with pyometraAnna Julia Rodrigues Peixotohttps://orcid.org/0000-0002-4861-7726Virgínia Conceição Tavares Limahttps://orcid.org/0000-0002-3535-5085Maria Eduarda dos Santos Lopes Fernandeshttps://orcid.org/0000-0003-1414-2475Lucinéia Costa Oliveirahttps://orcid.org/0000-0001-7445-6746Beatriz Teixeira Blanchttps://orcid.org/0000-0002-6025-8156Felipe Farias Pereira da Câmara Barroshttps://orcid.org/0000-0003-2071-6930Fabiana Batalha Knackfusshttps://orcid.org/0000-0003-4560-1339Cristiane Divan Baldanihttps://orcid.org/0000-0002-4627-1362Cássia Maria Molinaro Coelhohttps://orcid.org/0000-0003-1205-8413ABSTRACT: This retrospective study evaluated the impact of the clinical presentation of pyometra on the morbidity and mortality of the affected bitches. The medical records of 47 bitches surgically treated for pyometra between May and December 2017 were evaluated. The admission data were analyzed to classify the animals according to the clinical presentation of pyometra, presence of systemic inflammatory response syndrome (SIRS) and organic dysfunctions (cardiovascular, neurological, renal, and hemostatic). The outcomes were recorded for up to 14 days. The overall mortality rate was 13%. Open and closed pyometra were identified in 62% (n= 29) and 38% (n= 18) of the cases, respectively. The SIRS was present in 44 (94%) bitches, and 27 (57%) had at least one organ dysfunction. The most prevalent dysfunction was hemostatic, followed by neurological, cardiovascular, and renal dysfunction. The clinical presentation of pyometra and the presence of SIRS did not correlate with each other, or with the presence of organ dysfunction and mortality. However, cumulative organ dysfunction (r=0.532, P=<0.001) and the presence of neurological (r= -0.371; P=0.012) and renal dysfunction (r=0.303; P=0.041) were correlated with mortality. Thus, the identification of organ dysfunction through physical examination and routine laboratory analysis proved to be more effective in identifying and predicting the critically ill patients than the SIRS criteria or clinical presentation of the disease.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782024000100603&tlng=endogopen cervixclosed cervixkidney dysfunctionneurological dysfunction |
| spellingShingle | Anna Julia Rodrigues Peixoto Virgínia Conceição Tavares Lima Maria Eduarda dos Santos Lopes Fernandes Lucinéia Costa Oliveira Beatriz Teixeira Blanc Felipe Farias Pereira da Câmara Barros Fabiana Batalha Knackfuss Cristiane Divan Baldani Cássia Maria Molinaro Coelho The impact of clinical presentation, presence of SIRS and organ dysfunction on mortality in bitches with pyometra Ciência Rural dog open cervix closed cervix kidney dysfunction neurological dysfunction |
| title | The impact of clinical presentation, presence of SIRS and organ dysfunction on mortality in bitches with pyometra |
| title_full | The impact of clinical presentation, presence of SIRS and organ dysfunction on mortality in bitches with pyometra |
| title_fullStr | The impact of clinical presentation, presence of SIRS and organ dysfunction on mortality in bitches with pyometra |
| title_full_unstemmed | The impact of clinical presentation, presence of SIRS and organ dysfunction on mortality in bitches with pyometra |
| title_short | The impact of clinical presentation, presence of SIRS and organ dysfunction on mortality in bitches with pyometra |
| title_sort | impact of clinical presentation presence of sirs and organ dysfunction on mortality in bitches with pyometra |
| topic | dog open cervix closed cervix kidney dysfunction neurological dysfunction |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782024000100603&tlng=en |
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