Risk factors associated with actinic prurigo: a case control study
Abstract: Background: Actinic prurigo (AP) is an idiopathic photodermatosis. Although its initial manifestations can appear in 6 to 8-year-old children, cases are diagnosed later, between the second and fourth decades of life, when the injuries are exacerbated. Objective: To identify risk factors...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Dermatologia
2017-12-01
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| Series: | Anais Brasileiros de Dermatologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017000600774&tlng=en |
| _version_ | 1798019939970318336 |
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| author | Juan Carlos Cuevas-Gonzalez María Elisa Vega-Memíje Socorro Aída Borges-Yáñez Erika Rodríguez-Lobato |
| author_facet | Juan Carlos Cuevas-Gonzalez María Elisa Vega-Memíje Socorro Aída Borges-Yáñez Erika Rodríguez-Lobato |
| author_sort | Juan Carlos Cuevas-Gonzalez |
| collection | DOAJ |
| description | Abstract: Background: Actinic prurigo (AP) is an idiopathic photodermatosis. Although its initial manifestations can appear in 6 to 8-year-old children, cases are diagnosed later, between the second and fourth decades of life, when the injuries are exacerbated. Objective: To identify risk factors associated with clinical manifestations of AP such as skin and mucosal lesions. Methods: Thirty patients with AP and 60 controls were included in the study, the dependent variable was the presence of skin or labial mucosal lesions, the independent variables were age, sex, solar exposure, living with pets or farm animals, exposure to wood smoke, smoking habit, years smoking, and hours spent per day and per week in contact with people who smoke. Results: Of the 30 diagnosed AP patients, 66.7% were female. Patients age ranged from 7 to 71 years and the mean age was 35.77 ± 14.55 years. We found significant differences with the age and cohabitation with farm animals. Those who lived with farm animals presented 14.31 times higher probability of developing AP (95% CI 3-78.06). Study limitations: This is a case-control study; therefore, a causal relationship cannot be proven, and these results cannot be generalized to every population. Conclusions: The identification of factors related to the development of AP increases our knowledge of its physiopathology. Moreover, identifying antigens that possibly trigger the allergic reaction will have preventive and therapeutic applications in populations at risk of AP. |
| first_indexed | 2024-04-11T16:49:44Z |
| format | Article |
| id | doaj.art-32ad8c19e22543b5aa384aad93a23523 |
| institution | Directory Open Access Journal |
| issn | 0365-0596 |
| language | English |
| last_indexed | 2024-04-11T16:49:44Z |
| publishDate | 2017-12-01 |
| publisher | Sociedade Brasileira de Dermatologia |
| record_format | Article |
| series | Anais Brasileiros de Dermatologia |
| spelling | doaj.art-32ad8c19e22543b5aa384aad93a235232022-12-22T04:13:29ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05962017-12-0192677477810.1590/abd1806-4841.20175105Risk factors associated with actinic prurigo: a case control studyJuan Carlos Cuevas-GonzalezMaría Elisa Vega-MemíjeSocorro Aída Borges-YáñezErika Rodríguez-LobatoAbstract: Background: Actinic prurigo (AP) is an idiopathic photodermatosis. Although its initial manifestations can appear in 6 to 8-year-old children, cases are diagnosed later, between the second and fourth decades of life, when the injuries are exacerbated. Objective: To identify risk factors associated with clinical manifestations of AP such as skin and mucosal lesions. Methods: Thirty patients with AP and 60 controls were included in the study, the dependent variable was the presence of skin or labial mucosal lesions, the independent variables were age, sex, solar exposure, living with pets or farm animals, exposure to wood smoke, smoking habit, years smoking, and hours spent per day and per week in contact with people who smoke. Results: Of the 30 diagnosed AP patients, 66.7% were female. Patients age ranged from 7 to 71 years and the mean age was 35.77 ± 14.55 years. We found significant differences with the age and cohabitation with farm animals. Those who lived with farm animals presented 14.31 times higher probability of developing AP (95% CI 3-78.06). Study limitations: This is a case-control study; therefore, a causal relationship cannot be proven, and these results cannot be generalized to every population. Conclusions: The identification of factors related to the development of AP increases our knowledge of its physiopathology. Moreover, identifying antigens that possibly trigger the allergic reaction will have preventive and therapeutic applications in populations at risk of AP.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017000600774&tlng=enLipPhotosensitivity disordersRisk factorsSkin |
| spellingShingle | Juan Carlos Cuevas-Gonzalez María Elisa Vega-Memíje Socorro Aída Borges-Yáñez Erika Rodríguez-Lobato Risk factors associated with actinic prurigo: a case control study Anais Brasileiros de Dermatologia Lip Photosensitivity disorders Risk factors Skin |
| title | Risk factors associated with actinic prurigo: a case control study |
| title_full | Risk factors associated with actinic prurigo: a case control study |
| title_fullStr | Risk factors associated with actinic prurigo: a case control study |
| title_full_unstemmed | Risk factors associated with actinic prurigo: a case control study |
| title_short | Risk factors associated with actinic prurigo: a case control study |
| title_sort | risk factors associated with actinic prurigo a case control study |
| topic | Lip Photosensitivity disorders Risk factors Skin |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017000600774&tlng=en |
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