Testing the Role of Myeloid Cell Glucose Flux in Inflammation and Atherosclerosis

Testing the Role of Myeloid Cell Glucose Flux in Inflammation and Atherosclerosis

Summary: Inflammatory activation of myeloid cells is accompanied by increased glycolysis, which is required for the surge in cytokine production. Although in vitro studies suggest that increased macrophage glucose metabolism is sufficient for cytokine induction, the proinflammatory effects of increa...

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Bibliographic Details
Main Authors: Tomohiro Nishizawa, Jenny E. Kanter, Farah Kramer, Shelley Barnhart, Xia Shen, Anuradha Vivekanandan-Giri, Valerie Z. Wall, Jason Kowitz, Sridevi Devaraj, Kevin D. O’Brien, Subramaniam Pennathur, Jingjing Tang, Robert S. Miyaoka, Elaine W. Raines, Karin E. Bornfeldt
Format: Article
Language:English
Published: Elsevier 2014-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471400206X

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