Influence of Renal Function and Age on the Pharmacokinetics of Levofloxacin in Patients with Bone and Joint Infections

Influence of Renal Function and Age on the Pharmacokinetics of Levofloxacin in Patients with Bone and Joint Infections

Despite its efficacy and toxicity being exposure-related, levofloxacin pharmacokinetics in patients with bone and joint infections has been poorly described to date, so the possible need for a dose adjustment is unknown in this population. A prospective population pharmacokinetic study was conducted...

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Bibliographic Details
Main Authors: Gauthier Eloy, David Lebeaux, Manon Launay, Marie-Paule Fernandez-Gerlinger, Eliane Billaud, Emmanuel Douez, Jean-Luc Mainardi, Benjamin Bouyer, Vincent Jullien
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Antibiotics
Subjects:
levofloxacin
bone and joint infection
pharmacokinetics
glomerular filtration rate
Online Access:https://www.mdpi.com/2079-6382/9/7/401

Internet

https://www.mdpi.com/2079-6382/9/7/401

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