Graves’ hyperthyroidism in pregnancy: a clinical review
Abstract Background Graves’ hyperthyroidism affects 0.2% of pregnant women. Establishing the correct diagnosis and effectively managing Graves’ hyperthyroidism in pregnancy remains a challenge for physicians. Main The goal of this paper is to review the diagnosis and management of Graves’ hyperthyro...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2018-03-01
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| Series: | Clinical Diabetes and Endocrinology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s40842-018-0054-7 |
| _version_ | 1828808037504122880 |
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| author | Caroline T. Nguyen Elizabeth B. Sasso Lorayne Barton Jorge H. Mestman |
| author_facet | Caroline T. Nguyen Elizabeth B. Sasso Lorayne Barton Jorge H. Mestman |
| author_sort | Caroline T. Nguyen |
| collection | DOAJ |
| description | Abstract Background Graves’ hyperthyroidism affects 0.2% of pregnant women. Establishing the correct diagnosis and effectively managing Graves’ hyperthyroidism in pregnancy remains a challenge for physicians. Main The goal of this paper is to review the diagnosis and management of Graves’ hyperthyroidism in pregnancy. The paper will discuss preconception counseling, etiologies of hyperthyroidism, thyroid function testing, pregnancy-related complications, maternal management, including thyroid storm, anti-thyroid drugs and the complications for mother and fetus, fetal and neonatal thyroid function, neonatal management, and maternal post-partum management. Conclusion Establishing the diagnosis of Graves’ hyperthyroidism early, maintaining euthyroidism, and achieving a serum total T4 in the upper limit of normal throughout pregnancy is key to reducing the risk of maternal, fetal, and newborn complications. The key to a successful pregnancy begins with preconception counseling. |
| first_indexed | 2024-12-12T08:34:47Z |
| format | Article |
| id | doaj.art-32b2441127064baea0d3e8aadd609a2e |
| institution | Directory Open Access Journal |
| issn | 2055-8260 |
| language | English |
| last_indexed | 2024-12-12T08:34:47Z |
| publishDate | 2018-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Clinical Diabetes and Endocrinology |
| spelling | doaj.art-32b2441127064baea0d3e8aadd609a2e2022-12-22T00:30:59ZengBMCClinical Diabetes and Endocrinology2055-82602018-03-01411910.1186/s40842-018-0054-7Graves’ hyperthyroidism in pregnancy: a clinical reviewCaroline T. Nguyen0Elizabeth B. Sasso1Lorayne Barton2Jorge H. Mestman3Division of Endocrinology, Diabetes, & Metabolism, Department of Medicine, Keck School of Medicine, University of Southern CaliforniaDivision of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Keck School of Medicine, University of Southern CaliforniaDivision of Neonatology, Department of Pediatrics, LAC+USC Medical Center, Keck School of Medicine, University of Southern CaliforniaDivision of Endocrinology, Diabetes & Metabolism, Department of Medicine and Obstetrics and Gynecology, Keck School of Medicine, University of Southern CaliforniaAbstract Background Graves’ hyperthyroidism affects 0.2% of pregnant women. Establishing the correct diagnosis and effectively managing Graves’ hyperthyroidism in pregnancy remains a challenge for physicians. Main The goal of this paper is to review the diagnosis and management of Graves’ hyperthyroidism in pregnancy. The paper will discuss preconception counseling, etiologies of hyperthyroidism, thyroid function testing, pregnancy-related complications, maternal management, including thyroid storm, anti-thyroid drugs and the complications for mother and fetus, fetal and neonatal thyroid function, neonatal management, and maternal post-partum management. Conclusion Establishing the diagnosis of Graves’ hyperthyroidism early, maintaining euthyroidism, and achieving a serum total T4 in the upper limit of normal throughout pregnancy is key to reducing the risk of maternal, fetal, and newborn complications. The key to a successful pregnancy begins with preconception counseling.http://link.springer.com/article/10.1186/s40842-018-0054-7HyperthyroidismPregnancyAntithyroid drugsMethimazolePropylthiouracilTRAb |
| spellingShingle | Caroline T. Nguyen Elizabeth B. Sasso Lorayne Barton Jorge H. Mestman Graves’ hyperthyroidism in pregnancy: a clinical review Clinical Diabetes and Endocrinology Hyperthyroidism Pregnancy Antithyroid drugs Methimazole Propylthiouracil TRAb |
| title | Graves’ hyperthyroidism in pregnancy: a clinical review |
| title_full | Graves’ hyperthyroidism in pregnancy: a clinical review |
| title_fullStr | Graves’ hyperthyroidism in pregnancy: a clinical review |
| title_full_unstemmed | Graves’ hyperthyroidism in pregnancy: a clinical review |
| title_short | Graves’ hyperthyroidism in pregnancy: a clinical review |
| title_sort | graves hyperthyroidism in pregnancy a clinical review |
| topic | Hyperthyroidism Pregnancy Antithyroid drugs Methimazole Propylthiouracil TRAb |
| url | http://link.springer.com/article/10.1186/s40842-018-0054-7 |
| work_keys_str_mv | AT carolinetnguyen graveshyperthyroidisminpregnancyaclinicalreview AT elizabethbsasso graveshyperthyroidisminpregnancyaclinicalreview AT loraynebarton graveshyperthyroidisminpregnancyaclinicalreview AT jorgehmestman graveshyperthyroidisminpregnancyaclinicalreview |