Human umbilical cord mesenchymal stem cells and derived hepatocyte-like cells exhibit similar therapeutic effects on an acute liver failure mouse model.

Mesenchymal stem cells (MSCs) have exhibited therapeutic effects in multiple animal models so that are promising liver substitute for transplantation treatment of end-stage liver diseases. However, it has been shown that over-manipulation of these cells increased their tumorigenic potential, and tha...

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Autors principals: Ruiping Zhou, Zhuokun Li, Chengyi He, Ronglin Li, Hongbin Xia, Chunyang Li, Jia Xiao, Zhi-Ying Chen
Format: Article
Idioma:English
Publicat: Public Library of Science (PLoS) 2014-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC4125182?pdf=render