Efficacy and safety of PARP inhibitor maintenance therapy for ovarian cancer: a meta-analysis and trial sequential analysis of randomized controlled trials

Efficacy and safety of PARP inhibitor maintenance therapy for ovarian cancer: a meta-analysis and trial sequential analysis of randomized controlled trials

BackgroundThe landscape of poly (ADP-ribose) polymerase (PARP) inhibitor treatment for ovarian cancer (OC) is continually evolving. This research aimed to evaluate the efficacy and safety of PARP inhibitors compared to placebo as a maintenance therapy for OC patients.MethodsWe conducted a search of...

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Dettagli Bibliografici
Autori principali: Guojuan Sun, Yi Liu
Natura: Articolo
Lingua:English
Pubblicazione: Frontiers Media S.A. 2024-09-01
Serie:Frontiers in Pharmacology
Soggetti:
PARP inhibitors
olaparib
niraparib
rucaparib
placebo
ovarian cancer
Accesso online:https://www.frontiersin.org/articles/10.3389/fphar.2024.1460285/full

Accesso online

https://www.frontiersin.org/articles/10.3389/fphar.2024.1460285/full

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