VEGF promotes the transcription of the human PRL-3 gene in HUVEC through transcription factor MEF2C.

VEGF promotes the transcription of the human PRL-3 gene in HUVEC through transcription factor MEF2C.

Phosphatase of regenerating liver 3 (PRL-3) is known to be overexpressed in many tumors, and its transcript level is high in the vasculature and endothelial cells of malignant tumor tissue. However, the mechanism(s) underlying its enhanced expression and its function in endothelial cells remain unkn...

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Bibliographic Details
Main Authors: Jianliang Xu, Shaoxian Cao, Lu Wang, Rui Xu, Gong Chen, Qiang Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3206935?pdf=render

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