Effect of ENaC modulators on rat neural responses to NaCl.

Effect of ENaC modulators on rat neural responses to NaCl.

The effects of small molecule ENaC activators N,N,N-trimethyl-2-((4-methyl-2-((4-methyl-1H-indol-3-yl)thio)pentanoyl)oxy)ethanaminium iodide (Compound 1) and N-(2-hydroxyethyl)-4-methyl-2-((4-methyl-1H-indol-3-yl)thio)pentanamide (Compound 2), were tested on the benzamil (Bz)-sensitive NaCl chorda t...

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Bibliographic Details
Main Authors: Shobha Mummalaneni, Jie Qian, Tam-Hao T Phan, Mee-Ra Rhyu, Gerard L Heck, John A DeSimone, Vijay Lyall
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4026388?pdf=render

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