Peritoneal Dialysis for Potential Kidney Transplant Recipients: Pride or Prejudice?
Kidney transplantation (KT) is recognized as the gold-standard of treatment for patients with end-stage renal disease. Additionally, it has been demonstrated that receiving a pre-emptive KT ensures the best recipient and graft survivals. However, due to an overwhelming discrepancy between the organs...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-02-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/58/2/214 |
| _version_ | 1797478252851232768 |
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| author | Luca Nardelli Antonio Scalamogna Piergiorgio Messa Maurizio Gallieni Roberto Cacciola Federica Tripodi Giuseppe Castellano Evaldo Favi |
| author_facet | Luca Nardelli Antonio Scalamogna Piergiorgio Messa Maurizio Gallieni Roberto Cacciola Federica Tripodi Giuseppe Castellano Evaldo Favi |
| author_sort | Luca Nardelli |
| collection | DOAJ |
| description | Kidney transplantation (KT) is recognized as the gold-standard of treatment for patients with end-stage renal disease. Additionally, it has been demonstrated that receiving a pre-emptive KT ensures the best recipient and graft survivals. However, due to an overwhelming discrepancy between the organs available and the patients on the transplant waiting list, the vast majority of transplant candidates require prolonged periods of dialysis before being transplanted. For many years, peritoneal dialysis (PD) and hemodialysis (HD) have been considered competitive renal replacement therapies (RRT). This dualistic vision has recently been questioned by evidence suggesting that an individualized and flexible approach may be more appropriate. In fact, tailored and cleverly planned changes between different RRT modalities, according to the patient’s needs and characteristics, are often needed in order to achieve the best results. While home HD is still under scrutiny in this particular setting, current data seems to favor the use of PD over in-center HD in patients awaiting a KT. In this specific population, the demonstrated advantages of PD are superior quality of life, longer preservation of residual renal function, lower incidence of delayed graft function, better recipient survival, and reduced cost. |
| first_indexed | 2024-03-09T21:29:19Z |
| format | Article |
| id | doaj.art-32c91b446890470d8dbf136c7b943404 |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-09T21:29:19Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-32c91b446890470d8dbf136c7b9434042023-11-23T20:59:51ZengMDPI AGMedicina1010-660X1648-91442022-02-0158221410.3390/medicina58020214Peritoneal Dialysis for Potential Kidney Transplant Recipients: Pride or Prejudice?Luca Nardelli0Antonio Scalamogna1Piergiorgio Messa2Maurizio Gallieni3Roberto Cacciola4Federica Tripodi5Giuseppe Castellano6Evaldo Favi7Nephrology, Dialysis and Transplantation, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, 20122 Milan, ItalyNephrology, Dialysis and Transplantation, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, 20122 Milan, ItalyNephrology, Dialysis and Transplantation, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, 20122 Milan, ItalyDepartment of Biomedical and Clinical Sciences, Università di Milano, 20157 Milan, ItalyDepartment of Surgical Sciences, Università di Tor Vergata, 00133 Rome, ItalyNephrology, Dialysis and Transplantation, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, 20122 Milan, ItalyNephrology, Dialysis and Transplantation, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, 20122 Milan, ItalyDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, ItalyKidney transplantation (KT) is recognized as the gold-standard of treatment for patients with end-stage renal disease. Additionally, it has been demonstrated that receiving a pre-emptive KT ensures the best recipient and graft survivals. However, due to an overwhelming discrepancy between the organs available and the patients on the transplant waiting list, the vast majority of transplant candidates require prolonged periods of dialysis before being transplanted. For many years, peritoneal dialysis (PD) and hemodialysis (HD) have been considered competitive renal replacement therapies (RRT). This dualistic vision has recently been questioned by evidence suggesting that an individualized and flexible approach may be more appropriate. In fact, tailored and cleverly planned changes between different RRT modalities, according to the patient’s needs and characteristics, are often needed in order to achieve the best results. While home HD is still under scrutiny in this particular setting, current data seems to favor the use of PD over in-center HD in patients awaiting a KT. In this specific population, the demonstrated advantages of PD are superior quality of life, longer preservation of residual renal function, lower incidence of delayed graft function, better recipient survival, and reduced cost.https://www.mdpi.com/1648-9144/58/2/214kidney transplantationperitoneal dialysishemodialysispatient survivalallograft survivalrenal function |
| spellingShingle | Luca Nardelli Antonio Scalamogna Piergiorgio Messa Maurizio Gallieni Roberto Cacciola Federica Tripodi Giuseppe Castellano Evaldo Favi Peritoneal Dialysis for Potential Kidney Transplant Recipients: Pride or Prejudice? Medicina kidney transplantation peritoneal dialysis hemodialysis patient survival allograft survival renal function |
| title | Peritoneal Dialysis for Potential Kidney Transplant Recipients: Pride or Prejudice? |
| title_full | Peritoneal Dialysis for Potential Kidney Transplant Recipients: Pride or Prejudice? |
| title_fullStr | Peritoneal Dialysis for Potential Kidney Transplant Recipients: Pride or Prejudice? |
| title_full_unstemmed | Peritoneal Dialysis for Potential Kidney Transplant Recipients: Pride or Prejudice? |
| title_short | Peritoneal Dialysis for Potential Kidney Transplant Recipients: Pride or Prejudice? |
| title_sort | peritoneal dialysis for potential kidney transplant recipients pride or prejudice |
| topic | kidney transplantation peritoneal dialysis hemodialysis patient survival allograft survival renal function |
| url | https://www.mdpi.com/1648-9144/58/2/214 |
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