Association between self-perceived psychological stress and transitory ischaemic attack and minor stroke: a case–control study
Introduction: Stroke has a complex aetiopathogenesis influenced by numerous risk factors. There is growing interest in the study of the pathophysiological changes associated with stress and their potential relationship with cerebrovascular disease. The purpose of this paper is to assess the strength...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier España
2020-10-01
|
| Series: | Neurología (English Edition) |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2173580819301014 |
| _version_ | 1818228524860833792 |
|---|---|
| author | J.M. Ramírez-Moreno P. Muñoz Vega S. Espada S. Bartolomé Alberca J. Aguirre D. Peral |
| author_facet | J.M. Ramírez-Moreno P. Muñoz Vega S. Espada S. Bartolomé Alberca J. Aguirre D. Peral |
| author_sort | J.M. Ramírez-Moreno |
| collection | DOAJ |
| description | Introduction: Stroke has a complex aetiopathogenesis influenced by numerous risk factors. There is growing interest in the study of the pathophysiological changes associated with stress and their potential relationship with cerebrovascular disease. The purpose of this paper is to assess the strength of association between exposure to stress and stroke. Methods: We conducted a case–control study (1:1) to compare exposure to stress in a group of patients with a history of a first transient ischaemic attack (TIA) or minor stroke and in a control group. Participants were asked a subjective question about their perception of stress in the previous months and completed the standardised Effort-Reward Imbalance (ERI) questionnaire. Logistic regression models were used for data analysis. Results: The study included data on 50 cases and 50 controls. There were no significant differences in demographic variables and economic, social, and employment status between cases and controls. Fifty percent of the cases reported moderate to severe stress, compared to 30% of controls (OR: 2.33; 95% CI: 1.02-5.30; P = .041). ERI questionnaire results found that greater effort at work (OR: 1.48; 95% CI: 1.19-1.83) and greater commitment is associated with stroke (OR: 1.34; 95% CI: 1.17-1.54), while higher reward constitutes a protective factor against the disease (OR: 0.71; 95% CI: 0.61-0.82). Conclusions: There is a strong association between self-perceived psychological stress and TIA. The imbalance between effort and reward at work is also clearly related to TIA. Resumen: Introducción: El ictus tiene una etiopatogenia compleja en la que influyen un gran número de factores de riesgo. Existe un creciente interés por el estudio de los cambios fisiopatológicos que conlleva el estrés y su posible relación con la enfermedad cerebrovascular. El propósito de este trabajo es valorar la fuerza de asociación entre la exposición al estrés y el ictus. Método: Realizamos un estudio de casos y controles (1:1), comparando la exposición al estrés en un grupo de pacientes con antecedentes de un primer ataque isquémico transitorio o ictus minor, frente a un grupo control. Se realizó una pregunta subjetiva sobre la percepción de estrés en los últimos meses y se aplicó el cuestionario estandarizado Effort-Reward Imbalance (ERI). Para el análisis utilizamos modelos de regresión logística. Resultados: Incluimos 50 casos y 50 controles. No hubo diferencias significativas en las variables demográficas entre casos y controles, ni en nivel económico, situación social o laboral. El 50% de los casos refería situación de estrés moderada o grave frente al 30% de controles (OR: 2,33; IC95%: 1,02-5,30; p = 0,041). Cuestionario ERI: se observa que un mayor esfuerzo en el trabajo (OR: 1,48; IC95%: 1,19-1,83) y un mayor compromiso frente a una menor implicación laboral se asocia con el ictus (OR: 1,34; IC95%: 1,17-1,54); mientras que una mayor recompensa laboral tiene un factor protector (OR: 0,71; IC95%: 0,61-0,82). Conclusiones: Existe una fuerte asociación entre la percepción del estrés y el ataque isquémico transitorio. El desequilibrio entre el esfuerzo y la recompensa laboral también se relaciona claramente con el ataque isquémico transitorio. |
| first_indexed | 2024-12-12T10:04:05Z |
| format | Article |
| id | doaj.art-32cd9c3722644860b2002c1e75303206 |
| institution | Directory Open Access Journal |
| issn | 2173-5808 |
| language | English |
| last_indexed | 2024-12-12T10:04:05Z |
| publishDate | 2020-10-01 |
| publisher | Elsevier España |
| record_format | Article |
| series | Neurología (English Edition) |
| spelling | doaj.art-32cd9c3722644860b2002c1e753032062022-12-22T00:27:56ZengElsevier EspañaNeurología (English Edition)2173-58082020-10-01358556562Association between self-perceived psychological stress and transitory ischaemic attack and minor stroke: a case–control studyJ.M. Ramírez-Moreno0P. Muñoz Vega1S. Espada2S. Bartolomé Alberca3J. Aguirre4D. Peral5Departamento de Ciencias Biomédicas, Universidad de Extremadura, Badajoz, Spain; Centro de ictus, Sección de Neurología, Hospital Universitario Infanta Cristina, Badajoz, Spain; Grupo de Investigación Multidisciplinar de Extremadura GRIMEX, Spain; Corresponding author.Centro de ictus, Sección de Neurología, Hospital Universitario Infanta Cristina, Badajoz, SpainDepartamento de Ciencias Biomédicas, Universidad de Extremadura, Badajoz, SpainCentro de ictus, Sección de Neurología, Hospital Universitario Infanta Cristina, Badajoz, SpainDepartamento de Ciencias Biomédicas, Universidad de Extremadura, Badajoz, Spain; Centro de ictus, Sección de Neurología, Hospital Universitario Infanta Cristina, Badajoz, SpainDepartamento de Terapéutica Médico-quirúrgica, Universidad de Extremadura, Badajoz, SpainIntroduction: Stroke has a complex aetiopathogenesis influenced by numerous risk factors. There is growing interest in the study of the pathophysiological changes associated with stress and their potential relationship with cerebrovascular disease. The purpose of this paper is to assess the strength of association between exposure to stress and stroke. Methods: We conducted a case–control study (1:1) to compare exposure to stress in a group of patients with a history of a first transient ischaemic attack (TIA) or minor stroke and in a control group. Participants were asked a subjective question about their perception of stress in the previous months and completed the standardised Effort-Reward Imbalance (ERI) questionnaire. Logistic regression models were used for data analysis. Results: The study included data on 50 cases and 50 controls. There were no significant differences in demographic variables and economic, social, and employment status between cases and controls. Fifty percent of the cases reported moderate to severe stress, compared to 30% of controls (OR: 2.33; 95% CI: 1.02-5.30; P = .041). ERI questionnaire results found that greater effort at work (OR: 1.48; 95% CI: 1.19-1.83) and greater commitment is associated with stroke (OR: 1.34; 95% CI: 1.17-1.54), while higher reward constitutes a protective factor against the disease (OR: 0.71; 95% CI: 0.61-0.82). Conclusions: There is a strong association between self-perceived psychological stress and TIA. The imbalance between effort and reward at work is also clearly related to TIA. Resumen: Introducción: El ictus tiene una etiopatogenia compleja en la que influyen un gran número de factores de riesgo. Existe un creciente interés por el estudio de los cambios fisiopatológicos que conlleva el estrés y su posible relación con la enfermedad cerebrovascular. El propósito de este trabajo es valorar la fuerza de asociación entre la exposición al estrés y el ictus. Método: Realizamos un estudio de casos y controles (1:1), comparando la exposición al estrés en un grupo de pacientes con antecedentes de un primer ataque isquémico transitorio o ictus minor, frente a un grupo control. Se realizó una pregunta subjetiva sobre la percepción de estrés en los últimos meses y se aplicó el cuestionario estandarizado Effort-Reward Imbalance (ERI). Para el análisis utilizamos modelos de regresión logística. Resultados: Incluimos 50 casos y 50 controles. No hubo diferencias significativas en las variables demográficas entre casos y controles, ni en nivel económico, situación social o laboral. El 50% de los casos refería situación de estrés moderada o grave frente al 30% de controles (OR: 2,33; IC95%: 1,02-5,30; p = 0,041). Cuestionario ERI: se observa que un mayor esfuerzo en el trabajo (OR: 1,48; IC95%: 1,19-1,83) y un mayor compromiso frente a una menor implicación laboral se asocia con el ictus (OR: 1,34; IC95%: 1,17-1,54); mientras que una mayor recompensa laboral tiene un factor protector (OR: 0,71; IC95%: 0,61-0,82). Conclusiones: Existe una fuerte asociación entre la percepción del estrés y el ataque isquémico transitorio. El desequilibrio entre el esfuerzo y la recompensa laboral también se relaciona claramente con el ataque isquémico transitorio.http://www.sciencedirect.com/science/article/pii/S2173580819301014IctusAtaque isquémico transitorioEnfermedad cerebrovascularFactores psicosocialesEstrésMedicina del trabajo |
| spellingShingle | J.M. Ramírez-Moreno P. Muñoz Vega S. Espada S. Bartolomé Alberca J. Aguirre D. Peral Association between self-perceived psychological stress and transitory ischaemic attack and minor stroke: a case–control study Neurología (English Edition) Ictus Ataque isquémico transitorio Enfermedad cerebrovascular Factores psicosociales Estrés Medicina del trabajo |
| title | Association between self-perceived psychological stress and transitory ischaemic attack and minor stroke: a case–control study |
| title_full | Association between self-perceived psychological stress and transitory ischaemic attack and minor stroke: a case–control study |
| title_fullStr | Association between self-perceived psychological stress and transitory ischaemic attack and minor stroke: a case–control study |
| title_full_unstemmed | Association between self-perceived psychological stress and transitory ischaemic attack and minor stroke: a case–control study |
| title_short | Association between self-perceived psychological stress and transitory ischaemic attack and minor stroke: a case–control study |
| title_sort | association between self perceived psychological stress and transitory ischaemic attack and minor stroke a case control study |
| topic | Ictus Ataque isquémico transitorio Enfermedad cerebrovascular Factores psicosociales Estrés Medicina del trabajo |
| url | http://www.sciencedirect.com/science/article/pii/S2173580819301014 |
| work_keys_str_mv | AT jmramirezmoreno associationbetweenselfperceivedpsychologicalstressandtransitoryischaemicattackandminorstrokeacasecontrolstudy AT pmunozvega associationbetweenselfperceivedpsychologicalstressandtransitoryischaemicattackandminorstrokeacasecontrolstudy AT sespada associationbetweenselfperceivedpsychologicalstressandtransitoryischaemicattackandminorstrokeacasecontrolstudy AT sbartolomealberca associationbetweenselfperceivedpsychologicalstressandtransitoryischaemicattackandminorstrokeacasecontrolstudy AT jaguirre associationbetweenselfperceivedpsychologicalstressandtransitoryischaemicattackandminorstrokeacasecontrolstudy AT dperal associationbetweenselfperceivedpsychologicalstressandtransitoryischaemicattackandminorstrokeacasecontrolstudy |